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1.A.24.1.4
Connexin 35 hemichannels (activated by depolarization; deactivated by hyperpolarization; expressed in retina and brain (Valiunas et al., 2004).

Accession Number:Q8JFD6
Protein Name:Gap junction protein
Length:304
Molecular Weight:35060.00
Species:Danio rerio (Zebrafish) (Brachydanio rerio) [7955]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate small molecules

Cross database links:

eggNOG: fiNOG05498
HEGENOM: HBG717760
RefSeq: NP_919401.1   
Entrez Gene ID: 378444   
Pfam: PF00029    PF10582   
KEGG: dre:378444   

Gene Ontology

GO:0005922 C:connexon complex
GO:0016021 C:integral to membrane
GO:0055077 F:gap junction hemi-channel activity
GO:0005244 F:voltage-gated ion channel activity
GO:0007267 P:cell-cell signaling

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MGEWTILERL LEAAVQQHST MIGRILLTVV VIFRILIVAI VGETVYDDEQ SMFVCNTLQP 
61:	GCNQACYDKA FPISHIRYWV FQIIMVCTPS LCFITYSVHQ SAKQKERRYS TIYLSLDKDP 
121:	DTMRRDDSKK IKNTIVNGVL QNTENSTKES EPDCLEVKEI PNSAMRTTKS KMRRQEGISR 
181:	FYIIQVVFRN ALEIGFLVGQ YFLYGFNVPA VYECDRYPCI KDVECYVSRP TEKTVFLVFM 
241:	FAVSGICVVL NLAELNHLGW RKIKTAVRGV QARRKSIYEI RNKDLPRMSM PNFGRTQSSD 
301:	SAYV