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1.A.25.1.1
Invertebrate innexin, (gap junction protein), INX3

Accession Number:Q19746
Protein Name:INX-3 aka F22F4.2
Length:420
Molecular Weight:48917.00
Species:Caenorhabditis elegans [6239]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate small molecules

Cross database links:

eggNOG: meNOG24007
HEGENOM: HBG389069
RefSeq: NP_509002.2   
Entrez Gene ID: 180866   
Pfam: PF00876   
KEGG: cel:F22F4.2   

Gene Ontology

GO:0005921 C:gap junction
GO:0016021 C:integral to membrane
GO:0040007 P:growth
GO:0040011 P:locomotion
GO:0002119 P:nematode larval development
GO:0040010 P:positive regulation of growth rate
GO:0000003 P:reproduction

References (3)

[1] “eat-5 and unc-7 represent a multigene family in Caenorhabditis elegans involved in cell-cell coupling.”  Starich T.A.et.al.   8707836
[2] “Genome sequence of the nematode C. elegans: a platform for investigating biology.”  The C. elegans sequencing consortiumet.al.   9851916
[3] “Innexin-3 forms connexin-like intercellular channels.”  Landesman Y.et.al.   10381394

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MLGVPFIDRW LSETFKPKTF DDAVDRLSYV TTATLLAFFS IMVSCKQYVG SAIQCWMPME 
61:	FKGGWEQYAE DYCFIQNTFF IPERSEIPGD VEDRQKAEIG YYQWVPIVLA IQAFMFYLPS 
121:	WIWSSLYKQC GLDFPSVISE AEALRSQDSE TRTKGVNKLV DFIGDILDTR SKNEYGRFYC 
181:	YRFGKGLGSM TSMLYICIKL MYLANVFVQF IILNKFLGNE TFLWGFHTFA DLYAGREWQD 
241:	SGVFPRVTLC DFSVRKLANV HRYTVQCVLM INMFNEKIYL FIWFWFVFVL ITTFINTLCT 
301:	IYRLSFDSSR HNYIRSLLSG PVNNFKDEKA MIASFANNGL KQDGVLLMRF IDDHAGAMVT 
361:	KEICEELFKK HGENLQHNRD FHHGHSTKST SPGLEEGHHE HLYTPEKMKL MAPDYPIKHA