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1.A.25.1.2
Invertebrate innexin, UNC-7

Accession Number:Q03412
Protein Name:UNC-7 aka R07D5.1
Length:522
Molecular Weight:60121.00
Species:Caenorhabditis elegans [6239]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate small molecules

Cross database links:

eggNOG: meNOG08667
HEGENOM: HBG389069
RefSeq: NP_510515.1   
Entrez Gene ID: 181608   
Pfam: PF00876   
KEGG: cel:R07D5.1   

Gene Ontology

GO:0005921 C:gap junction
GO:0016021 C:integral to membrane
GO:0040011 P:locomotion

References (2)

[1] “Molecular and genetic analysis of unc-7, a Caenorhabditis elegans gene required for coordinated locomotion.”  Starich T.A.et.al.   7681023
[2] “Genome sequence of the nematode C. elegans: a platform for investigating biology.”  The C. elegans sequencing consortiumet.al.   9851916

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MLGSSSNPEP PLLSRIIGVP PPPPPRAPTT ALVLRVPTVD SPSKKKQQPD TRNKYQETAL 
61:	RDKKTRTPLE KARHLDNLPS YQAQKLLDGS HQLRIDSHHV GSAGHGAGQG HGHKKEFGPA 
121:	MILYYLASAF RALYPRLDDD FVDKLNYYYT TTILASFALL VSAKQYVGFP IQCWVPATFT 
181:	DAMEQYTENY CWVQNTYWVP MQEDIPREIY SRRNRQIGYY QWVPFILAIE ALLFYVPCIL 
241:	WRGLLYWHSG INLQGLVQMA CDARLMDSEI KTRTVYTMAR HMQDEVQLTN IDRQGHSRSC 
301:	FSNLQLGANC GRHCGCYVTM LYIGIKVLYS ANVLLQFFLL NHLLGSNDLA YGFSLLKDLM 
361:	HAIEWEQTGM FPRVTLCDFE VRVLGNIHRH TVQCVLMINM FNEKIFLFLW FWFLTCGIVT 
421:	VCNTMYWILI MFIPSQGMSF VRKYLRVLPD HPAKPIADDV TLRKFTNNFL RKDGVFMLRM 
481:	ISTHAGELMS SELILALWQD FNNVDRSPTQ FWDAEHGQGT ID