TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


1.A.25.1.3
Invertebrate innexin, Ogre

Accession Number:P27716
Protein Name:INX1 aka Ogre aka L(1)OGRE aka CG3039
Length:362
Molecular Weight:42582.00
Species:Drosophila melanogaster (Fruit fly) [7227]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate small molecules

Cross database links:

eggNOG: inNOG05833
DIP: DIP-22933N
RefSeq: NP_524824.1    NP_727147.1   
Entrez Gene ID: 45382   
Pfam: PF00876   
BioCyc: DMEL-XXX-02:DMEL-XXX-02-000904-MONOMER    DMEL-XXX-02:DMEL-XXX-02-000905-MONOMER   
KEGG: dme:Dmel_CG3039   

Gene Ontology

GO:0005921 C:gap junction
GO:0016021 C:integral to membrane
GO:0005515 F:protein binding
GO:0007602 P:phototransduction

References (3)

[1] “Molecular cloning and analysis of l(1)ogre, a locus of Drosophila melanogaster with prominent effects on the postembryonic development of the central nervous system.”  Watanabe T.et.al.   1963867
[2] “The genome sequence of Drosophila melanogaster.”  Adams M.D.et.al.   10731132
[3] “Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.”  Misra S.et.al.   12537572

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MYKLLGSLKS YLKWQDIQTD NAVFRLHNSF TTVLLLTCSL IITATQYVGQ PISCIVNGVP 
61:	PHVVNTFCWI HSTFTMPDAF RRQVGREVAH PGVANDFGDE DAKKYYTYYQ WVCFVLFFQA 
121:	MACYTPKFLW NKFEGGLMRM IVMGLNITIC TREEKEAKRD ALLDYLIKHV KRHKLYAIRY 
181:	WACEFLCCIN IIVQMYLMNR FFDGEFLSYG TNIMKLSDVP QEQRVDPMVY VFPRVTKCTF 
241:	HKYGPSGSLQ KHDSLCILPL NIVNEKTYVF IWFWFWILLV LLIGLIVFRG CIIFMPKFRP 
301:	RLLNASNRMI PMEICRSLSR KLDIGDWWLI YMLGRNLDPV IYKDVMSEFA KQVEPSKHDR 
361:	AK