TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


1.A.25.1.6
Innexin-14 (Protein Opu-14)

Accession Number:O62136
Protein Name:Innexin-14
Length:434
Molecular Weight:50982.00
Species:Caenorhabditis elegans [6239]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate small molecules

Cross database links:

eggNOG: NOG276207
DIP: DIP-24670N
Entrez Gene ID: 172488   
Pfam: PF00876   
KEGG: cel:F07A5.1   

Gene Ontology

GO:0005921 C:gap junction
GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0055077 F:gap junction hemi-channel activity
GO:0005216 F:ion channel activity
GO:0006915 P:apoptotic process
GO:0008340 P:determination of adult lifespan
GO:0009792 P:embryo development ending in birth or egg hatching
GO:0019915 P:lipid storage
GO:0000003 P:reproduction

References (1)

[1] “Genome sequence of the nematode C. elegans: a platform for investigating biology.”  The C. elegans sequencing consortiumet.al.   9851916

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MIWEIPIIGD FITKPFKAAK LYEFYDRLHL FTVYLLGFFV LLTGAKQHFG NPIDCMLPKQ 
61:	HDDLKSWRDY IHNFCLFYGT FRYDVSNGTS EFGSYTEDAS VNYYQWVPFF FAFQVCCFLL 
121:	PFWCWAYMQK LIYIDMAFIV DYSGKINSEK TFEKTKEKVD RIVNYMHDHF KFRRAHKMGY 
181:	LSWITFNSAF PSVLYSLTKL FFITNVIIQV NLVCKFLDVD SWTWGFDLLG KFIHPTPRAP 
241:	EFSSFSDKQR FAAILTDGSY NRFQYFPILV GCEYQLQESV SNFVNHKAQC IIPMNVINEK 
301:	IFIGLYFWLL VLTALSVIGT VKWILRIKSK KLNEVMIYKL IKKSLEREPF DSNIHDHRYN 
361:	FVHKYLCADG ILLIYFMMDT NGFLKTEEVI GALFKKYCSD AGLEPLQTAP TLTSSPRDLA 
421:	YSETNYGFAA PQKI