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1.A.26.1.4
Mg2+, Co2+ transporter, MgtE

Accession Number:Q52398
Protein Name:MgtE
Length:356
Molecular Weight:38494.00
Species:Providencia stuartii [588]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Mg2+, Co2+

Cross database links:

Pfam: PF00571    PF01769   

Gene Ontology

GO:0016020 C:membrane
GO:0008324 F:cation transmembrane transporter activity
GO:0005247 F:voltage-gated chloride channel activity
GO:0006812 P:cation transport
GO:0006821 P:chloride transport
GO:0055085 P:transmembrane transport
GO:0003824 F:catalytic activity

References (6)

[1] “Cloning and characterization of MgtE, a putative new class of Mg2+ transporter from Bacillus firmus OF4.”  Smith R.L.et.al.   7868596
[2] “Distribution of the CorA Mg2+ transport system in gram-negative bacteria.”  Smith R.L.et.al.   7883724
[3] “Cloning of the mgtE Mg2+ transporter from Providencia stuartii and the distribution of mgtE in gram-negative and gram-positive bacteria.”  Townsend D.E.et.al.   7665526
[4] “Cloning and characterization of MgtE, a putative new class of Mg2+ transporter from Bacillus firmus OF4.”  Smith R.L.et.al.   7868596
[5] “Distribution of the CorA Mg2+ transport system in gram-negative bacteria.”  Smith R.L.et.al.   7883724
[6] “Cloning of the mgtE Mg2+ transporter from Providencia stuartii and the distribution of mgtE in gram-negative and gram-positive bacteria.”  Townsend D.E.et.al.   7665526

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTFTTQNKAG SVAIAQSAMK GARLNNNNTQ QPKIDDATVS AYMSQSYLPV SIADSVACVK 
61:	KNLIEHLDGE QIPTYLFVVD QENYLNGILS VKSLLAADEG LLVSDIMRHN YFSVAPDQSR 
121:	HDVYDLINHS GLDMIPVVQF GKLMGVLRPQ DIAELIEDEN TLDAQLQGAT TPLEEPYLAT 
181:	SPITLWRKRV VWLLMLFVAE AYTGTVLKAF EEQLEAAISL AFFIPLLIGT GGNSGTQITS 
241:	TLVRAMALGE VSLRNLGAVL KKEVSTSFLV AVTIGAAALI RAWILGVGAE VTIVVSLTIV 
301:	AITMWSAIVS SIIPMVLKKL KVDPAVVSAP FIATFIDGTG LIIYFEIAKL VMTEFA