TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


1.A.27.1.2
Cl- conductance inducer protein, Mat-8

Accession Number:Q61835
Protein Name:Mat-8 aka FXYD3 aka MAT8 aka PLML
Length:88
Molecular Weight:9526.00
Species:Mus musculus (Mouse) [10090]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Membrane1 / Single-pass type I membrane protein2
Substrate Cl-

Cross database links:

Genevestigator: Q61835
HEGENOM: HBG444253
RefSeq: NP_032583.1   
Entrez Gene ID: 17178   
Pfam: PF02038   
KEGG: mmu:17178   

Gene Ontology

GO:0034707 C:chloride channel complex
GO:0005254 F:chloride channel activity
GO:0006811 P:ion transport

References (3)

[1] “neu and ras initiate murine mammary tumors that share genetic markers generally absent in c-myc and int-2-initiated tumors.”  Morrison B.W.et.al.   7970700
[2] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[3] “Mat-8, a novel phospholemman-like protein expressed in human breast tumors, induces a chloride conductance in Xenopus oocytes.”  Morrison B.W.et.al.   7836447

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MQEVVLSLLV LLAGLPTLDA NDPENKNDPF YYDWYSLRVG GLICAGILCA LGIIVLMSGK 
61:	CKCKFRQKPS HRPGEGPPLI TPGSAHNC