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1.A.27.1.4
The sterol (dexamethasone, aldosterone) and low NaCl diet-inducible FXYD domain-containing ion transport regulator 4 precursor (Channel inducing factor, CHIF). An IsK-like MinK homologue (Attali et al., 1995).

Accession Number:Q63113
Protein Name:FXYD domain-containing ion transport regulator 4 aka CHIF
Length:87
Molecular Weight:9084.00
Species:Rattus norvegicus (Rat) [10116]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Membrane1 / Single-pass type I membrane protein2
Substrate anions

Cross database links:

Genevestigator: Q63113
eggNOG: roNOG17752
RefSeq: NP_071783.1   
Entrez Gene ID: 64190   
Pfam: PF02038   
KEGG: rno:64190   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005267 F:potassium channel activity
GO:0005515 F:protein binding
GO:0006811 P:ion transport

References (2)

[1] “A corticosteroid-induced gene expressing an 'IsK-like' K+ channel activity in Xenopus oocytes.”  Attali B.et.al.   7597086
[2] “Cellular localization and regulation of CHIF in kidney and colon.”  Capurro C.et.al.   8843704
Structure:
2JP3     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MEGITCAFLL VLAGLPVLEA NGPVDKGSPF YYDWESLQLG GMIFGGLLCI AGIAMALSGK 
61:	CKCRRNHTPS SLPEKVTPLI TPGSAST