TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


1.A.28.2.1
The dimeric urea transporter, Utp (urea flux is saturable, could be inhibited by phloretin, and was not affected by pH; Raunser et al., 2009)

Accession Number:Q9S408
Protein Name:Utp
Length:300
Molecular Weight:32669.00
Species:Actinobacillus pleuropneumoniae (Haemophilus pleuropneumoniae) [715]
Number of TMSs:9
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Urea

Cross database links:

Pfam: PF03253   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0015204 F:urea transmembrane transporter activity
GO:0015840 P:urea transport

References (1)

[1] “Novel genes affecting urease acivity in Actinobacillus pleuropneumoniae.”  Bosse J.T.et.al.   11157936

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MKLLKSTLTG VGQIFLQENG LSGLVIVIAM FFSHWTLGVG CFLGALIGTY TASLLKYPQR 
61:	QIEQGLYGFN ASLAFMCVMF TFGLVDASNP MIWLNAVSAS IVATLIMREF TKRNKIAFTF 
121:	PFVFTCWIFC GAIAKYHFFD LSQTTPALAD NTNTLQAIGE PFYAWAEVNF GSSIITGILL 
181:	FLAISINSPM AAMYGLAAAT IGTSFANQLL TVQPNQLANG IYGFSPILVA CAFAGDRFRN 
241:	FVYIILGSLL AVLIQFSISS LGIPSYTIGF IIASWLLLAV KSKLDKAAFD KNKLVRLLNP