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1.A.29.1.5
Urea transporter channel (UreI) (pH-sensitive)

Accession Number:Q93PJ3
Protein Name:Urease accessory protein UreI
Length:170
Molecular Weight:19090.00
Species:Helicobacter hepaticus [32025]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Urea

Cross database links:

HEGENOM: HBG369044
RefSeq: NP_859940.1   
Entrez Gene ID: 1493463   
Pfam: PF02293   
BioCyc: HHEP235279:HH_0409-MONOMER   
KEGG: hhe:HH0409   

Gene Ontology

GO:0016020 C:membrane
GO:0006810 P:transport

References (2)

[1] “Cloning, expression, and catalytic activity of Helicobacter hepaticus urease.”  Beckwith C.S.et.al.   11500473
[2] “The complete genome sequence of the carcinogenic bacterium Helicobacter hepaticus.”  Suerbaum S.et.al.   12810954

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MLGIVLMYVA IVLINNGICR LTHIDGKSAS IMNIFVGLLS VLVNLIVIVH GSINSEYNDF 
61:	YAAATGLLFG FTYLFIACNN LFNLDIRAYG WYSLFVAINA IPAAYLSYLE NTQEGMAFAL 
121:	IWIAWGILWL TGWIESILKI ELKFVPYLAI AEGILTAWIP AWLILMGYWH