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1.A.3.1.4
Ryanodine receptor (RyR) of 5107 aas.  Flubendiamine, a RyR-activating insecticide, induced Ca2+ release in hemocytes (Kato et al. 2009; Wu et al. 2013).

Accession Number:R9R5D5
Protein Name:Ryanodine receptor
Length:5107
Molecular Weight:578230.00
Species:Pieris rapae (Small white butterfly) [64459]
Number of TMSs:4
Substrate Ca2+

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MAEAEGGASE QDDVSFLRTE DMVCLSCTAT GERVCLAAEG FGNRHCFLEN IADKNIPPDL 
61:	SQCVFVIEQA LSVRALQELV TAAGSETGKG TGSGHRTLLY GNAILLRHLN SDMYLACLST 
121:	SSSQDKLASD VGLQEHSQGE ACWWTLHPAS KQRSEGEKVR VGDDLILVSV ATERYLHTTK 
181:	ENEVSIVNAS FHVTHWSVQP YGTGISRMKY VGYVFGGDVL RFFHGGDECL TIPSTWNKDG 
241:	GLNIVVYEGG SVMSQARSLW RLELARTKWA GGFINWYHPM RIRHITTGRY LGVNDQNELY 
301:	LVSREEATTA SCAFCLRQEK NDQKVVLEDK DLEVIGAPII RYGDSTVIVQ HSETGLWLSY 
361:	KSYETKKKGL GKVEEKQAIL HEEGKMDDGL DFSRSQEEES RTARVIRKCS SLFTKFINGL 
421:	ETLQENRRHS MFFASVNLGE MVMCLEDLIN YFAQPEEDME HEEKQNRFRA LRNRQDLFQE 
481:	EGILNLILEA IDKINVITSQ GFLAGFLAGY ESGQSWDMIS VYLYQLLAAI IKGNHTNCAQ 
541:	FANSNRLNWL FSRLGSQASG EGTGMLDVLH CVLIDSPEAL NMMRDEHIKV IISLLEKHGR 
601:	DPKVLDVLCS LCVGNGVAVR SSQNNICDYL LPGKNLLLQT ALVDHVSSVR PNIFVGRVEG 
661:	SAVYQKWYFE ATMDHIEKTT HMMPHLRIGW ANTSGYVPYP GGGEKWGGNG VGDDLYSFGF 
721:	DGAYLWSGGR KIQVNKTHAE EPFIRKGDVI GCALNLTVPI INFMFNGVKV TGSFPNFNLE 
781:	RNVLPCHELS SKLKLPFSHG KRTTGRAKDT PGLPEGYSPL VESLLPQQIL NLEPCFYFGN 
841:	LSKRALAGPP LVQDDTAFVP TPVDTASITL SSYIEQIRDK LAENIHEMWA MNKIEAGWMY 
901:	GDQRDDLHKV HPCLVPFERL PAAEKRYDIQ LAVQTLKTIL ALGYYISLDK PPARIRNVRL 
961:	PNEPFMQSNG YKPAPLDLSA VTLTPKMDEL VDQLAENTHN LWARERIQQG WTYGLNEDPD 
1021:	MNRSPHLVPY PKVDDAIKKA NRDTASETVR TLLVYGYNLD PPTGEQHEAL LAEASRQKQA 
1081:	EFRTYRAEKN YAVSSGKWYF EFEILTAGPM RVGWAHADMP PGMMLGQDEN SWAFDGYNEE 
1141:	KVYSGSLESF GKQWAVGDVV GVFLDLIDKT ISFSLNGELL MDALGGETTF ADVQGDNFVP 
1201:	ACTLGVGQKA RLSYGQDVNS LKYFTTCGLQ EGYEPFCVNM NRDVTHWYTK DQPMFENTDE 
1261:	MIDTRIDVTR IPAGSDTPPC LKISHNTFET MEKANWEFLR LSLPVICHAE FIDESEKARR 
1321:	WVEIKDRQQI LMKEAVEAQM PAHIDQIMRS GFTMNDIKGL HYDENQEDVK IKRQPSRPPR 
1381:	KGSITRNVTI QNYNSQSGQN GMNRSTSEAE MSKYELGVQN LPEDTKKDKR GRSPFKFFRS 
1441:	KRGESGDRGK SRKSKTPDPY TDTEVSPDRA RRPNPQIRIS QANQRYNMQN RNDGANIYDS 
1501:	QGALSTNLTV PTPTQDRKQM TTATLDKSAT ETIGNEIFDA DCLKLINGYF YGVRIFPGQD 
1561:	PTHVYIGWVT TQYHLHSKDF NQNKVTKSSV IITDDYDRVI ESVNRQSCYM VRADELYNEV 
1621:	MAEATAKGAS QGMFIGCSVD TSTGTVSFTC EGKDTSIKFK MEPETKLFPA IFVEATSKEI 
1681:	LQIELGRSST SLPLSAAVLP TSDKHVNPQF PPRLKVQCLK PHQWARVPNQ FLQVHALKLS 
1741:	DIRGWSMLCE DAVSMLALHI PEEDRCIDIL ELIEMDKLLS FHAHTLTLYA ALCYQSNYRA 
1801:	AHALCQHVDQ KQLLYAIRSQ YMSGPLRQGF YDLLIALHLE SHATTMEACK NEFVIPLGPE 
1861:	LKALYEDREM CHSLRSLQTE SVRPQMNMTN IAENISDISN LYFPYFPLEV VREFVMQALA 
1921:	EAVETNQVHS RDPTGGSNEN LFLPLIKLVD RLLLVGMMRD EDVEKLLIMI NPETWDPTFD 
1981:	KEGKDEHRKG LLHMKMAEGA KLQMCYLLQH LNDIQLRHRV ESIIAFAHDF VGELQTDQLR 
2041:	RYTEIKQSDL PSAVAAKKTR EFRCPPREQM NAILSFKHLE DEDPENCPCG EELIARMNDF 
2101:	HDALMSHVSL SALQEPDGDQ SNEPEVKPGA FGKLYNIINT VKELEDDAKA LEEEKKKTPE 
2161:	EKFRKVLIQT IVNWAEESRI ETPKLVREMF SLLVRQYDAV GELIRALEKT YVINAKTKLD 
2221:	VAEMWVGLSQ IRALLPVQMS QEEEELMRKR LWKLVNNHTF FQHPDLIRVL RVHENVMAVM 
2281:	MNTLGRRAQA QSDAPATSPP TPEDKEKDTS HEMVVACCRF LCYFCRTGRQ NQKAMFDHFD 
2341:	FLLENSNILL ARPSLRGSTP LDVAYSSLME NTELALALRE HYLEKIAVYL SRCGLQSNSE 
2401:	LIEKGYPDLG WDPVEGERYL DFLRFCVWVN DESVEENANL VIRLLIRRPE CLGPALRGEG 
2461:	EGLLKAIVDA NKMSERIADR RKLRDLEQEG DISFSHPLPE SEDDEDYIDT GAAILNFYCT 
2521:	LVDLLGRCAP DAGVIALGKN ESLRARAILR SLVPLEDLQG VLSLRFTLNN PAAGEERPKS 
2581:	DMPSGLIPGH KQSVGLFLER VYGIETQELF YRLLEEAFLP DLRAATMLDR NDGCESDMAL 
2641:	SMNRYIGNSI LPLLIKHANF YNEAENYASL LDATLHTVYR LSKNRMLTKG QREAVSDFLV 
2701:	ALTSAMQPSM LLKLLRKLKL TVDVSRLSEY TTVALRLLTL HYERCAKYYG STGGQGSYGS 
2761:	SSDEEKRLTM MLFSNIFDSL SKMDYEPELF GKALPCLIAI GCALPPDYSL SKNYDDEFYG 
2821:	KDSQASGADN PQYDPQPINT SSVALNNDLN TIVQKFSEHY HDAWASRKIE NGWVYGENWS 
2881:	DSQKTHPRLK PYNMLNDYEK ERYKEPVRES LKALLAIGWS VEHSEVDIPS NNRSSMRRQS 
2941:	KSGIDSATPF NYNPHPVDMT NLTLSREMQN MAERLADNAH DIWAKKKKEE LVTSGGGIHP 
3001:	QLVPYDLLTD KEKKKDRERS QELLKYLQYQ GYKLHRPSKA SQIDTEQTTT GVAIELRFAY 
3061:	SLLEKLIQYI DRATINMKLL KPSTTFSRRS SFKTSTRDIK FFSKVVLPLM EKYFSTHRNY 
3121:	FIAVATATNN VGAASLKEKE MVAALFCKLA SLLRSRLAAF GPDVRITVRC LQVLVKGIDA 
3181:	KPLVKNCPEF IRTSMLTFFN NLADDLGHTI FNLQEGKYAH LRGTHLKTST SLGYINGVML 
3241:	PILTAMFDHL ANCEYGADLL LDEIQVASYK MLGSSYTLGT DVTLTHDRKY LKTEIERHKP 
3301:	ALGSCLGAFS STFPVAFLEP HLNKHNQFSL LNRIADHSLE AQDIMAKMEQ SMPTLETILN 
3361:	EVDHFVESDK TYSEAPHIID VVLPLLCSYL PFWWAQGPDN VTPTGGNHVA MVTADHMNQL 
3421:	LKNVLKLIKK NIGNENAPWM TRIATYTQQI IINSSEELLR ESFLPLAERV RKRTDNMFHK 
3481:	EESLRGFIKS STDDTSQVES QIQEDWQLLV RDIYSFYPLL IKYVDLQRNH WLRNNVPEAE 
3541:	ELYNHVAEVF NIWSKSQYFL KEEQNFISAN EIDNMVLIMP TATRRVTTVV DGTQQGGGKK 
3601:	KKKHRDKKRD KDKEVQASLM VACLKRLLPV GLNLFAGREQ ELVQHCKDRF LKKMSEQDVA 
3661:	EFAKTQLTLP DKIDPADEMS WQHYLYSKLG SKSKTAITVE TSENKVKIID DTVERIVAMS 
3721:	KVLFGLHMID HPQQMSKNVY RSVVSIQRKR AVIACFRQTS LHSLPRHRAC NIFARTYYEL 
3781:	WVEEENIGQE VMIEDLTQTF EDAELKKSDI VEEEGKPDPL TQLVTTFCRG AMTERSGALQ 
3841:	EDPLYMSYAH IIAKSCGEEE EEGGEEEEGG GEPEGEDEGK SSIHEQEMEK QKLLFHQARL 
3901:	ANRGVAEMVL LHISASKGVP SDMVMKTLQL GISILRGGNI DIQMGMLNHL KDKKDVGFFT 
3961:	SIAGLMNSCS VLDLDAFERN TKAEGLGVGL EGAAGEKNMH DAEFTCALFR FIQLTCEGHN 
4021:	LEWQNYLRTQ AGNTTTVNVV ICTVDYLLRL QESIMDFYWH YSSKELIDPA GKANFFKAIG 
4081:	VASQVFNTLT EVIQGPCTQN QQALAHSRLW DAVGGFLFLF SHMQDKLSKH SSQVDLLKEL 
4141:	LNLQKDMITM MLSMLEGNVV NGTIGKQMVD TLVESASNVE LILKYFDMFL KLKDLTSSAS 
4201:	FKEIDANNDG WVLPKDFKEK MEQQKSYSPE EIEFLLACCE TNHDGKLDYI GFCDRFHEPA 
4261:	KEIGFNLAVL LTNLSEHMPN EPRLARFLET AGSVLNXFEP FLGRIEIMGG SKRIERVYFE 
4321:	IKESNIEQWE KPQIKESKRA FFYSIVTEGG DKEKLEAFVN FCEDAIFEMT HASGLMAASE 
4381:	ESASGPKNRE AAYTYLGDDD DERAGKDPFR RGYQSVKDAI AATFSFLSPS NIKAKIADMQ 
4441:	QMPPAELLVG FLKLFFYLFY YIGYGFVVVI RYIFGVLLGL MRGPHVEEPP PQEPTEEEKI 
4501:	GPSRHLPALP ATDDTGQMQV SAFGLDITKE DNGQLQVKPH ESPTTSTPSS GEEAEVSPDE 
4561:	SIEHTEEQQP PSLIDLLGGE QAKKQAQERV EAQAAQQAAM SAIEAESKKA VQVPAPSALS 
4621:	QVDLSQYTKR AVSFLARNFY NLKYVALVLA FCINFVLLFY KVSIPDSDKE GSGIGDIISG 
4681:	SGSGQGSGSG EGSGESEDDD SLEVVRIDED FFYMEHVIKM AAALHSIVSL AILIGYYHLK 
4741:	VPLAIFKRGK DIARRLEFDG LYIAEQPEDD DLKSHWDKLV ISAKSFPVNY WDKFIKKKVR 
4801:	AKYSETYDFD SISNMLGMEK TSFSAQEDEG NKGLWNYIVN IDWRYQVWKA GVTITDNSFL 
4861:	YSLWYFSFSV MGNFNNFFFA AHLLDVAVGF KTLRTILQSV THNGKQLVLT VMLLTIIVYI 
4921:	YTVIAFNFFR KFYVQEEDDE INRNCHDMLS CFVFNLYKGV RAGGGIGDEL EPPDGDDSEV 
4981:	YRIIFDISFF FFVIIILLAI LQGLIIDAFG ELRDQLESVK EDMESNCFIC GINKDYFDKV 
5041:	PHGFDTHVQR EHNLANYMFF LMHLINKPDT EYTGQETFVW NMYTQRCWDF FPVGDCFRKQ 
5101:	YEDVMGE