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1.A.3.1.6
Ryanodine-sensitive calcium release channel receptor, RyR of 5071 aas and 6 putative TMSs.  The tissue lecalization has been described (Hamada et al. 2002).  Required for neuronal regeneration (Sun et al. 2014).

Accession Number:P91905
Protein Name:Ryanodine receptor
Length:5071
Molecular Weight:576362.00
Species:Caenorhabditis elegans [6239]
Number of TMSs:6
Substrate Ca2+

Cross database links:

External Searches:

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  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MADKEEQGGG EQDDVSFLRT GDIVCLSCVA SHNRDGVLGS ERVCLCTEGF GNRMCTLENV 
61:	SDKDIPPDIA MCMLYIDNAL SMRALQEMMS ADSDHKSASG AGGHKTLLYG HAVQLKHVQS 
121:	EMYLACLSSC SSNDKLAFDV GVQETNEGEA CWWTIHPASK QRSEGEKVRV GDDVILVSVA 
181:	TERYLHMAYS KGYMVIASFH QTLWNIQSVS SGSMRTRNMG FLFGNDVLRL FHGNDECLTI 
241:	PENWSEHPQH NMVIYEGGAA VTQARSLWRV ELIRMKWHGA LVGWEQVFRI KHITSGRYLG 
301:	VLDNSVQLYH KEKADFDLTA FVMCQNKDPK KQMLDEKEEE GMGNATIRYG ETNAFIQHVK 
361:	TQLWLSYQTT EVTKKGLGKV EEKKAVALKD GHMDDCYTFF MALEEESKSA RVIRKCSSVL 
421:	NKFLKGIDAL QLEGNQSTDW TRVDLNEVLK LMEDLIEYFA QPNDEQDFEE KQNHLRALRS 
481:	RQDLFQEEGV LNMILDTIDK FSQMEALPDF AGLIGEETHV KWEQISTYLY LLVAAMIKGN 
541:	HYNCAQFASA QRLDWLFGRL SNPQSAEGIL DVLYCVLTES PEALNMINEG HIRSVISLLE 
601:	KVGRDPKVLD VLSSLCEGNG MAVRSSQNLI TQYLLPGKDL LLQTSMRDHV SSMMPNVMLG 
661:	VVEGSALFRK WYFEAEVEHI ETMTKQTPYL RIGWANSVGF KPFPGSGDKM GCNGVGDDFY 
721:	SYGFDGKSMY FGGKSRRVGH KLLEKGDVIG CSIDLTIPEI KFSVNGTYMS GSFKKFNIDG 
781:	YFFPVMSLSA KVSCRFILGG NQGRLRYGPP TGFSAVVEAV NGELQITDCL SFGDLGKNIF 
841:	SGPQTIFNNL EPFIPTPIDV SATQLNHHAT EMHQKYAENL HELWAMRKIE LGWSYGETRS 
901:	ETSRKHPCLT KFEYLPETEK KYNILLALTT MKTIEALGYH LITEDPPCRL RAVRLGPNFQ 
961:	QQNGYKPGPL DTHEIQLPAE LQPLTEALAR NTHNIWAKEK IKRGWTFGLS EHVDATQKRS 
1021:	PHLVPYEQVD ERIKQANRES AAENIRALQL FGIFLEPPAH EHDEVAEKEL RARKDNTRTY 
1081:	RAEATYAVCG GKWYFEFEIL TAGYMKIGWM DIGSTPEIQL GADDRSYAFD GYLGRKWHQG 
1141:	AETYGKEWKI GDVVGCFLDL NDRTISFSLN GELLLDPSGS EMAFDNVVCG DGLVPAMTLG 
1201:	SGQRGRLNFG QQSNSLKFFT TCGLQEGYEP FCVNMYRTMP MWFAKHFPRF EDISTLKSGS 
1261:	ILEVSRIPAT GNSPPCLKIL QKVTISEGGP SEKAKMEYIK LSLPVKCNDT FVKNKDKETI 
1321:	RRQLQEYKPR SQSVVSQIRA PGIPKEFDDN KEKKGFLRSM LGSKDSHESD DDRRSRTNSK 
1381:	QPSVDGDEPP AVRRSLLELP HDERQIAEDS MRDLNDRHSE KPKKGGLLSR LRDSSNTRKN 
1441:	FRDSDRRKEE KAAQLRQMKA NSRSFDAGSL DTSTLPTGQK DVLASSEMPL SGPGRQLTIK 
1501:	RSSIKKNKKG KKAEIALEKM EREKKGSIIP MDAQLDVLQE GDAHALVHHK DKVDEYYYGI 
1561:	RIFPGQDPSQ VWVGWVTTQY HYYNVNFDGS QGVRKCRFSE ADHHGTTVDS VQSQNCYMVN 
1621:	VSELLATTPD VANTKVSGTL IGCIIDTSIG ELSFQVGSTD TGIKFKLEPG AMLFPAAFVT 
1681:	PTATEILQFE LGRIKYTFPL SAAMFKSCEK SLVPFCPPRL TVEQIESVYW ARVPNETLRT 
1741:	TALKLSEVRG WSVLCNDPVR IMSVYIPEKD QSLDILEMIE MPDMLEFHRQ TLNLYCKLAS 
1801:	HGNHKVAHTL CQHIDEDQIM YAIKSHYLSG PMRQGFHDLL IGLHLMSHTA ARNSMAKEYV 
1861:	IPLVPQLQIK NVLDPDSESR YPQITGESVS MLSQMASEPV KKHVSREDEM KLLPPSVDFE 
1921:	ALKKHVMESL QSATHHAVMN CRDLIGGDNT NHFEPLFKLF DQLLVIGLIN DEELECLLRL 
1981:	IHPQAFDENY ETGTTQKGLT QLELAEPVKI QLVSILDHLC DIQLRYRIES LVAFTEGFVG 
2041:	ELQSDQCKRY MEIKQTDMPP AEAAKKTKEF RCPPKEQMFR LLMCKVKEER DPELMEEDAD 
2101:	VDQCPMAEGL QQQLRDFCEL LVGKIGNVKE GDSDDQLALI ESEEGSWVDS FARIVVKVPP 
2161:	PVLEEGMEMQ KKGTQNFREI IVTMLREWAQ ADFIESKSLI RNMFRLLLRQ YSGIREIRDA 
2221:	MSQTYVFHER NEKDVTDFLV YLIQIRELLT VQFEHTEEAI LKRGLWKLMN NRIFFQHPDL 
2281:	MRLLSVHENV MSIMMNILTA QQGTVEHEGD ELKEKAPIKD ASEMVVACSR FLCYFCRTSR 
2341:	QNQKAMFEHL SFLLDNATML LARPSLRGSV PLDVAYSSFM DNNELALALK EEELDKVAVY 
2401:	LSRCGLQPNS ELITKGYPDI GWDPVEGERY IDFLRFCVWI NGENVEENAN LVIRLLIRRP 
2461:	ECLGVALKGE GQGLFSAFKE AIALSEDIRL LENDSHPSLL SSGLLGENPT YPSKDAEGED 
2521:	YIDLGAATLD FYSSLVDLLA KCAPDPMAIQ AGKGDSLRAR AILRSLISLD DLGQILALRF 
2581:	TIPNLAAPSI EDTGPLPGLL PNHKGSVLLF LDRVYGIDQQ DMLFHVLEQS FLPDLRAATM 
2641:	MDSPRALESD TALALNRYLC NSVLPLLTNH SHFFADAEHH SALLDATLHT VYRMNRLKSL 
2701:	TKNQRDAVSD FLVAITRELP PAMMIKLLKK VITDILTMND MNVLVPLRLI TLHYERCGKY 
2761:	YGSGNHYGVA SEQEKRLSML LFDAIFDTLG SRPYDPELFG KALPCMTAIG SAISPDYTLT 
2821:	SGLEDVRNKR REEEGAWIPR TVDVSRCEIN RDLEKMTELF AEHFHDSWAS RKLEKGWVHG 
2881:	DLYSRANFTH PRLKPFALLK DFEKSFYKER CSECLKALMA WNYSFEMMDR DANDRASAAR 
2941:	TLSGTSISNF APKPIDLSSM TLEKDMVNAA EKMAEHSHLI WAKKVMNDLN TKGGFMPIPL 
3001:	VPWDLLTDFE RRKDRFRASE ILKFLQYHGY HVNCPKDEQS QNDRLKSEGE RTSVEKRFAY 
3061:	NLLEKLITYL EQASLKMKSV KPSQELTRRN SFKKEGQDVK FFEKVVLPLM HAYFNAHKNY 
3121:	FLEGSSIVQT GTASNKEKEM VANLFCRLAA LLRIKNRAFG SVAKITVKCL QGLTQALDLR 
3181:	TLVKVNSDIV RTSLLTFFNN CADDLYASVN ELKDGGQYSL IRGQALKSWN SFEFANQMIV 
3241:	PVLTTMFAHL ARNHFGTDLL LDDIQAACYK ILDSLYMVTG LSSSISHRKS ISGESEKHRP 
3301:	GLGQCLAAFA SCFPVAFLEP EFNKSNKFSV LAKSQDQSVQ VQEMLQNLST HIPHLEKLLT 
3361:	DLETVANNNT MYSDVPNVYD VDLPLMCSYM AHWFSVGPDG KRDKEDQRAS VVQTTSVSCD 
3421:	HINRIFNALL KMIRNHVGIE NAPWLCRVNF FAVQIIQNVT SDPVREFVLP IAERLRRMSE 
3481:	KAYKEEEHMR THPDDADEGT VAEDNARLVR DTYAFFPILM KYTDLHRAQW LKTPTWETDG 
3541:	VYENVAVIFR IWSQSQHFKR EELNYVAQFE EDAAATGGGD MKTGKAAIAE RKKKRREGQI 
3601:	KKDKHAASIV IACLKRLLPV GLNVFGGREL DIVQQSKEKF IQKETEEKIR EFIKGLLEIP 
3661:	VKTDPTDKNA WQLSLYRKIG KSQMRGKDEM SQDAVIEKIF NMGQVSAILH TMTSRMEKED 
3721:	IWKKVLTLQR KRMAISLITA SHLYKTELHR GINFFLPAFS RLWMEEEDAG QDQLIADICS 
3781:	GVEEEEGPRI EIIMEEGVPI VASSEDTKEK ETNPDPLKQL IRCFQRAATS EETAASAIHE 
3841:	DSLYIRFADV MAKSIHIEEE DGEDGEEGEI DQAAKEEQSQ ALRGEQAVLA SRGAAIMCLM 
3901:	YLSASGGEPN EMVAQTLQLG IHLLSGGNVE IQKMLIEYLQ LKKDVRFFTS MAGLMNKCSV 
3961:	LNLEMFERQI KAEGLGMGAE LASGDNQNLN DADFTCSLFR FLQLTCEGHN LEFQNYLRTQ 
4021:	PGHTTSVNLI NCTVDYLLRL QESVMDFYWH YSSKEVIDEG GKEYFLRAIQ VCSQVFNTLT 
4081:	ESIQGPCVGN QMTLANSRLW DAINGFFFLF AHMMEKLYKN STQLELLREF LNLQKDMIVL 
4141:	MLSMLEGNVL NGSIGKQMVD ALVESQPSVE KILKFSDMFL KLKDLTTSQA FQDFDTNQDG 
4201:	WISPKEFQRA MESQKMYTVE DITYLMMCTD VNNDGKVDYM EFTERFHNPA RDIGFNLAVL 
4261:	LVNLKEHITN DPRLEKIIEK AQTLLEYFDP FLGRIEIMGS SKRVEKIYFE IQESWLEQWG 
4321:	KQQIRDSKNS FLFNVLQDDG GDQGKLEAFI NFCEDTIFEM QHAAAISSGD SDTKMERAIK 
4381:	QRDYFLQQTS ADHISETFKS GYNYGISAAS ALSPQNISTT MRNVSSSVRQ MSWTQLLYAV 
4441:	IILFIRAGLA IGWAGYLLLM TIFRFGYFLT TSSEEEEAAR QEKEQAKMNN EHPSFNPPII 
4501:	QEFHHSHVGV TAFGVGMNAD HLNVNSLPDF VPPERPETPE TVLEEEKPLN QETSPPTSPT 
4561:	SPASKAPSIY ESIGAPQMVQ LQSEADFQQG QYEPKIAESN STKSRGSILN MLARNFKTIE 
4621:	KITLYLAFFI NVILLFHRVD ISHAENAEAA SEGDDDEDAL ESIFITGMQF PYVEYEITGW 
4681:	MLAQILYWIS VLHLSTSFAL LVSFYQLKIP LITFKREKEI ARKLMFDGCW ITEEDSEELG 
4741:	IVDTFMWYLD RIVVSAKSFP MMYWDKFVRR KTRSKFKDQV DEETLTSILG EEKMSTDSSY 
4801:	DYRYSCWLWI GVILTNGQFL YRVGYLLCSA CGVFLSPFFY AFHLIDVVLS FPMLKAILQS 
4861:	VTHNLQQLIL TIMMTLVVVY LYTVIAFNFF RKFYVQEGEE GEEPDRKCHN MLTCFIYHFY 
4921:	AGVRAGGGIG DELESPYGDD LEYPRMFYDI SFFFFVIIIL LAIMQGLIID AFGELRDQQE 
4981:	SATEKLESSC FICDIGKETF DRMPRGFEIH TTKEHNFANY LFFLQHLVNK DETEYTGQET 
5041:	YVREKYDNRD WDFFPVGECF VKQYEDQLLQ S