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1.A.3.1.7
Aphid ryanodine receptor RyR) of 5105 aas and 6 TMSs, a target of insecticides.  The sequence of the Acyrthosiphon pisum (Pea aphid) is provided below, but the Toxoptera citricida (98% identiy; Brown citrus aphid; Aphis citricidus) RyR was studied (Wang et al. 2015).

Accession Number:X1WXB1
Protein Name:Uncharacterized protein
Length:5101
Molecular Weight:579963.00
Species:Acyrthosiphon pisum (Pea aphid) [7029]
Number of TMSs:6
Substrate Ca2+

Cross database links:

External Searches:

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  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MADSEGSSEQ DDVSFLRTED MVCLSCTATG ERVCLAAEGF GNRHCYLENI ADKNIPPDLS 
61:	QCVFVIEQAL SVRALQELVT AASSQEGKGG TGSGHRTLLY GNAILLRHQN SDMYLACLST 
121:	SSSNDKLSFD VGLQEHSQGE ACWWTVHPAS KQRSEGEKVR VGDDLILVSV ATERYLHTAK 
181:	ENELSVVNAS FHVTHWSVQP YGTGISRMKY VGYVFGGDVL RFFHGGDECL TIPSSWSDVS 
241:	GQNIVIYEGG SVMSQARSLW RLELARTKWA GGFINWYHPM RIRHLTTGRY LGVNENNELH 
301:	LVCREEATTA SSTFFLRQEK DDQKIILEDK DLEVIGAPII KYGDSTVLVQ HSDTGLWLTY 
361:	KSYETKKKGV GKVEEKQAVL HEEGKMDDGL DFSRSQEEES RTARVIRKCS SLFTQFISGL 
421:	ENLQSNRRSS LFCSFVNLNE MVMCLEDLIN YFAQPEEDME HEEKQNRFRA LRNRQDLFQE 
481:	EGILNLILEA IDKVNIITSQ GFMVSLAGDE SGQSWDVISG YLYQLLAAII KGNHTNCAQF 
541:	ANTNRLNWLF SRLGSQASSE GTGMLDVLHC VLIDSPEALN MMKDEHIKVI ISLLEKHGRD 
601:	PKVLDVLCSL CVGNGVAVRS SQNNICDFLL PGKNLLLQTL LVDHVASVRP NIFVGHVSGS 
661:	AVYRKWYYEV AIDHVEQTTH LNPHIRIGWA NTAGYVPYPG GGEKWGGNGV GDDLYSFGFD 
721:	GSYLWTGGRK SEVMPGTQIS NIKKSDVIGC ALDLTIPIIT FTLNGQLVQG AFRDFNLDGM 
781:	FFPVISCSSK VSCRFLLGGD HGRLKFTPPD EFSPLFETLL PQQILTIDPC FYFGNLNKCV 
841:	LTGPWYVEDD TAFVPNPVDT SMVTLPSYIE NIKDKLAENI HEMWAMNKIE AGWQYGDKRN 
901:	DTRKFHPCLI QFDKLPPAEK RYDSQLAVQT LKTVIALGYH ISIDNPPSRI KTVRLPNEPF 
961:	MQSNGYKPAP LDLSAIILSG KMEELIDQLA ENTHNLWAKE RIQQGWTYGL NEELQMLRSP 
1021:	HLVPYSKVDD AIKKANRDTA SETVRTLLVY GYNLDPPTGE TNEATLLTDD NTNRYLTFRT 
1081:	YRAEKTYAVS SGKWYFEFEI LTSGPMRVGW ARFTCSPGYQ IGSDENSWAF DGYNEEKIYM 
1141:	GTAESFGRQW QVGDVVGVFL DLMDHTISFS MNGELLMDTL GGETTFSEVQ GEGFVPAFTL 
1201:	GLGQKAKLTF GQDVNSLKYF TTCGLQEGYE PFCVNMKRPV TYWYTKDQPI FENTDDFSSV 
1261:	IDVTRIPAGS DTPPCLKISH NTFETMEKAN WEFLRLSLPV ICLPSFIDEQ EKQRRWQEIR 
1321:	IRQHRLLSQS EHATPAHIEQ IMKSGFSMSD IKGLHRGYSD DPVENDEMMP NATPLPPRGK 
1381:	NQPPPPRPPR KGSLSRHDDL TIENEGKLNR SSSELNFNIY NHQNGDGQDI NKDDKKKRGR 
1441:	SPFRFFSRKK EGPSDNPKRA KTPDPVRNVD RSRNAAHRPN TLNERVTPQI RVSQMDLKLV 
1501:	PPAIPDRPGG PKAMSFTPTS AGIEFVGNEI FDLECLKLIN EYYYGVRIFP GQDPTHVYVG 
1561:	WVTTQYHLHT KDFSQNHVRK STVTIVDEHN RILESIDRQS CYMVRSDELY NEVTNDSSGK 
1621:	GASQGMAIGC FIDIATGMMS FTCEGKETSF KFKMEPDIKL FPAIFVEASS KEILQIELGR 
1681:	TSTTLPLSAA VLQNSERHVL PQFPPRLKVQ CLRPHQWARV PNDSLHIHTL KLSDIRGWSI 
1741:	LCEDPVSMIA LHIPEEDRCI DILELIEMEK LLSFHAHTLT LYAAVCYQAN YRAAHILCTH 
1801:	VNQKQLLYAI CSEYMSGPLR QGFYDLLIAL HLESHATTME VCKNEYIIPL GHELTTLYDD 
1861:	PQMGHSLRSL QTESVRPQMK MTEISDVIDN VRNLYSPYFP LQVVREYVMA ALEEAVLVNQ 
1921:	VHNRDPIGGS NENLFLPLLK LVDRLLLVGM LRDEDVEKLL IMINPETWDP EFQKDGPDEH 
1981:	RKGLLHMKMA EGAKLQMCYL LHHLCDIQLR HRVESIISFS YQFVNDIQID QLRRYNEIKQ 
2041:	SDLPSAVAAK KTREFRCPPR EQMNAILGFK NLDSDDKENC LIGDDLRERM NEFNEKLMKQ 
2101:	ISLVALQESE DDKSDLNNLN NEGKIKQFYN FINAVKDEGN EDGLNEQEKK IPEEIFRKVL 
2161:	ISTIVSWAEE TQIETPKLVR EMFSLLVRQY DSVGELIRAL EKTYVINFKT KEDVAQMWVG 
2221:	LSQIRSLLPV QMSQEEEELM RERLWKLVNN HTFFQHPDLI RVLRMHENVM AVMMNTLGRR 
2281:	AQAQSQPGGT PVTGQDGEIV PKEKDTSHEM VVACCRFLCY FCRTSRQNQK AMFDHFSFLL 
2341:	ENSNILLSRP SLRGSTPLDV AYSSLMENTE LALALREHYL EKIAIYLSRC GLQSNSELIE 
2401:	KGYPDLGWDP VEGERYLDFL RFCVWVNGES VEENANLVIR LLIRRPECLG PALRGEGEGL 
2461:	LRAIIDANKM SERITERRKF LEESGNQENI QLDHPLPESD EDEDYIDTGA AILNFYCTLV 
2521:	DLLGRCAPDS SVISLGKNES LRARAILRSL VPLEDLHGVL SLRFTLQNPA AGQDRPKSDM 
2581:	PSGLIPGHKQ SVVLFLERVY GIEMQELFFT LLEEAFLPDL RTATMLDRND GLESDMALAM 
2641:	NRYIGNSVLP LLIGHSKFYS ESDNYANLLD ATLHTVYRLS KNRMLTKGQR EAVSDFLVAL 
2701:	TSQMQPSMLL KLLRKLTVDV SNLSEYTTVA LRLLTLHYDR CAKYYGSTGG QGIYGASSDE 
2761:	EKRLTMMLFS NIFDSLSKMD YDPELFGKAL PCLSAIGCAL PPDYSLSKNH DDEWYGSKQN 
2821:	IQGPSDGPYN PQPINTNSIV LDNDLNSIVH KFSEHYHDAW ANRKLENGWV YGEQFNDVNK 
2881:	SHPRLKPYMM LSEYEKELYK EPVRESLKAL LAIGWSIEHS ENDAPLNNRG SVRRQSKSNE 
2941:	NVTPFDYHPN PIDMTNLTLT REMQNMAERL AENSHDIWAK KKKEEVMLCG GGIHNQLVPY 
3001:	DLLTDKEKKK DRERSQEFLK YLQYQGYKLH RPNRNGGPSE AEQLAAASTG ELRFSYSLLE 
3061:	KLIHYIDRAS INMKLLKPSG TFSRRSSFKI CTRDIKFFSK VVLPLVEKYF STHRNYFITV 
3121:	ATASSVLGAA SLKEKEMVAS LFCKLANLLR SKLMAFGADV RITVRCLQVL VKAIDAKSLV 
3181:	KNCPEFIRTS MLTFFHNIAD DLEHTIQNLH DSRYCYLRGT HLKTSTSLFY VNDVILPVLS 
3241:	SLFDHLAAYE YGNELLLNEI QVAAYKMLSS LYTLGTDTSL THDRKYLKVQ LERHRPAFGS 
3301:	CLGAFSSTFP VAFLEPHLNK HNQYSLLNRF ADSSLEAQDI MSRMEGTMPT LETVLNEVDQ 
3361:	FIESEKTYAD APHIIDVILP LLCSYLPYWW AQGPDNVALT TGNHVTMVTS EHMNCLLKNV 
3421:	LKLIKKNIGN DNAPWMTQIA AYTQQIIINS SEELLKDPFL PLAERVKKRT ETLYHKEESL 
3481:	RGFIKSSTDD TSQIEAQIQE DWQLVVRDIY AFYPLLIKYV DLQRNHWLRN NISNAEDLYN 
3541:	HVSEIFNIWS KSQYFLREEQ NFISANEIDN MILIMPTATR RSAVISETSL GGSTGKKKKK 
3601:	HRDKKRDKEK EIQASLMVAC LKRLLPVGLN LFAGREQELV QHCKDRFLKR MPDYDVIQFV 
3661:	KIQLTLPDKL DPADEMSWQH YLYSKLGSKK GTTEIKPQQV DEVADRIVAM AKVLYGLHMI 
3721:	DHPQLQSKAI YRSVVSTQRK RAVIACFRQL SLHALTRHRA VNIFVRSFYE LWLQDENIGQ 
3781:	EVMIEDLTQS FEEAELKKRD KEEEEGMADP LNQMVTTFCR GAMTERSGAL QEDPLYMSYA 
3841:	DILAKSCGEE EEEGNNEEEG STGNGEEEGG ASIHEQEMEK QKLLFHQARL ANRGVAEMVL 
3901:	LHISACKGIP SEMVMKTLQL GIAVLRGGNL EIQMGMLNHL KEKKDVGFFT SVAGLMNSCS 
3961:	VLDLDAFERN TKAEGLGVGS EGAAGEKNMH DAEFTCTLFR FIQLTCEGHN LEWQNYLRTQ 
4021:	AGNTTTVNVV ICTVDYLLRL QESIMDFYWH YSSKELIDPA GKANFFKAIG VASQVFNTLS 
4081:	EVIQGPCTQN QQALAHSRLW DAVGGFLFLF SHMQDKLSKH SSQVDLLKEL LNLQKDMITM 
4141:	MLSMLEGNVV NGTIGKQMVD TLVESASNVE LILKYFDMFL KLKDLTSSAS FTEIDPNNDG 
4201:	WVHPKDFKEK MEQQKSYTAE EIEFMLQCCE SNHDGKIDYI GFTDQFHEPS KEIGFNLAVL 
4261:	LTNLSEHMPN EPRLTRFLET ASSVLNYFQP FLGRIEILGG SKRIERVYFE IKESNIEQWL 
4321:	KPQIRESKRA FFYSIVTEGG DKEKLEAFVN FCEDAIFEMQ HASGLMAVDD GSGIGGGKSR 
4381:	KTAYTYMADD EENKTAKDPI RRGIQAIKYG FHLLFFVLSP TNIKNKINEI QQMSVIELIT 
4441:	SFFKLWFYLI FYTGYSGVYV LRYISRILMQ LMSGTQSEET TVEVVEEKSG SFRMLPALPS 
4501:	SGMDEPPSTL TDGNNMRKNS GSPDSKHLKS NSVGDDKDET SAENHEKEDG VDGSEQQASF 
4561:	VDLLVGESAR KDSIAGPEVL AQQQAVMAAV EAEIKQKNSV ENPSAFSTID INAYTHRALS 
4621:	FLARNFYNLK YVALVLAFCI NFILLFYKVT TLADDLSDDG DVKEFALGSA GISNDDMDDS 
4681:	NSTEIADDEG VLELVHVNED FFYMAHVMRL AALLHSLASL AMLIAYYHLK VPLAIFKREK 
4741:	EIARRLEFDG LYIVEQPEDD DIKSHWDKLV ISAKSFPVNY WDKFAKKKVR QKYSETYDFD 
4801:	SISNLLGMEK TSFSTQENEE RTGLINFVIN IDWRYQVWKA GVTITDNAFL YSLWYFTFSI 
4861:	LGNFNNFFFA AHLLDVAVGF KTLRTILQSV THNGKQLVLT VLLLTIIVYI YTVIAFNFFR 
4921:	KFYVQEEDDE VDKKCHDMLT CFVFHLYKGV RAGGGIGDEI GSPDGDDYEV YRIMFDITFF 
4981:	FFVIIILLAI IQGLIIDAFG ELRDQLESVK EDMESNCFIC GIGKDYFDKV PHGFDTHVQE 
5041:	EHNLANYMFF LMHLINKPDT EYTGQETYVW NMYQQRCWDF FPVGDCFRKQ YEEELGGGGG 
5101:	V