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1.A.3.2.11
Calcium release channel IV3b, CRCIV3b, of 3127 aas.  Display structural and functional properties of ryanodine receptors (Ladenburger et al. 2009).  Localized to the alveolar sacs of the cortical subplasmalemmal Ca2+-stores (Plattner et al. 2012).  Involved in exocytosis in response to ryanodine receptor agonists (Docampo et al. 2013).

Accession Number:G7ZUA3
Protein Name:Calcium-release channel IV-3b
Length:3127
Molecular Weight:368989.00
Species:Paramecium tetraurelia [5888]
Number of TMSs:6
Substrate Ca2+

Cross database links:

External Searches:

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  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTDLPPIPNL RKQSLLGAEN YIPQTHNIIP LPQIVENVKP QKRNFNLKVG DIIYFKSYLS 
61:	DDFKGVISGD GIASNKLECI QVLGKNKLQD VQSQKSLQCK VGSLSFQKSL FQIITGKKYL 
121:	YQNQYKEEKE KPIDTIREIA ADETYQMELD KLTSDYDKRL EEFQKKCEEE INENERLYNH 
181:	LYGSNIVYGQ EIQLLHIYSG CTLSLNSDIL AKENCCRELS LEEIPNLNSN FRILSMNSVK 
241:	NPGEPILYGD QIIVQNSNQS QWNLGIQKPS AKFEKKDGLE VNASEQAYPL KISSYIDNKT 
301:	EEEINKQQIK GKYLQSGDVV SIKNRYLGGY LCIKRIQRIT DGLDKKPLII KDYETNINYA 
361:	INQFYFDVDK IRNEKINQMY QLYVDTSPKA DEELNSLWQV QHVDSLIYSR PTYESVFLIR 
421:	HVCTGLFLQI TNYGVGLTYD GLKMECQINL KSKKTSNDTI SYSEACKIQS AMNFQVDNYV 
481:	AQESVVVVCL EETKVAVQRK SQKQNIERAT FLFKQTSQDL SKISFRLNSL QEYLIKFYIF 
541:	LQDWGVVKSI EQNQQNQEEK RKYEYYEAFN NQKSLFDEIL QLFQTLDNLK MYLTNEGKPQ 
601:	SNEQLQQKQK ALMDNDIINL LFAIQRLCNC MIYGNLRENN KTIQEKSPSK IAKMKLDPIV 
661:	TQTQKINCIQ EIYSLLSLCV QSNPETSNYV LSLEMNKESI LDFLLQQLKH QREHVSKLIK 
721:	ESVRYTDMSD TKASIKKWVN ELQPLTEDNI EDQALYIEIL SLMMIDPYEN PNSLCQDSCR 
781:	RLLFGTRRKP DSSLPFQKAL IALDIYEENQ NYYPVVQFSP KREKGMLLQL SHQFGQNNPT 
841:	FCQLYLRFVE RQIKVAQRFI TRRPPLVDVT IDFFTTEALK ENQLVKQEDL KTVMPIFLKY 
901:	ENYLMNVMDL YSSLCKGRNQ KSIKCLMKNC FLNEKFLEIC LKRQQNIKTE LRFERTLIEL 
961:	FCNLYLDIDP LIKVSQFDNK CYLNDDLDQF DIQNQSGVYF YENNATKQLK RNEEYQKFLN 
1021:	QKEAKAEHQY MKLYASKMLS RKQINDVRIY YLEIFTQIDY PDHFRVQEFS GNLLQTQKST 
1081:	INQINIDYKR LAYYQLQYFL GILQIVKNSI DLGYNQLDEN QRIFSILPNI FVALILQQRP 
1141:	DNKIHKFKEN ENFESNLYKL SQSIEKNVWV TTYLPTAQQL QEQRKSKHKK QDKSSKQSEQ 
1201:	IIRQDIQFQR NWILQFLIWT FQYCTDDLLK MKIYLEGLQI LKIFGFLKLN LQILEFLFSK 
1261:	QQLNESNLSS PSSRDLDQFE FNNNEIDNNI QEEQIKKQKT PAQKAIFNVF KEPDGNRFSA 
1321:	LLFSCLLSSE KRNKLNEELL QILIDNFHAP KNSTNEIKEV EIIDNLMELK YFSIINGNSN 
1381:	TVQIISPKEA QILTKRATKY IQNSKRRKNA QKRVTSFDSL KNYQSKIIEQ FEQFFKPNSQ 
1441:	EVQYLKSFQN IVRNAGVHLV FLQFLVKPQN ICSTPDIVQF YKKLILFFEY FTKDNETNIA 
1501:	ILAQNEYLYK LLDIIQVDQQ DAEDWYYVPI KITKLVVQLL STIPVSEHDN FIINVFERIE 
1561:	KLGAELMQSE EFFVNAFSLR DVYFERKVTP RKKHLDAVAY FSLIQYLRIL RSLTKTFETP 
1621:	AEQSPLNKHL ILSSILKNDF LRIVLEPVNY YKKLLVPGQE QEEQNGTDSL YYHRIKLHAQ 
1681:	LIILITDCCQ YYRLGIQEMQ RIILYEQLKS ILLNSNSEYI VKRAYLQCLF ELYINQAKEG 
1741:	EFMNDTVESD EVRDILSRII IPELDQKQIC KFLEGLAKLI NQDKNKKVTQ KDLREQIARQ 
1801:	KRNYFEKRLS IDSTSEKEIG ILRDCSEFWT YLRKNVYTYD EMKDRIDIEN PENSNLSDEF 
1861:	AIIKQNVQKI KEIFNVLERD FRVKKEDLDL DDYRELIISI EEIIPQRKIT KFGQNFRIGF 
1921:	IQDKNTDKLL FDKYDTLKED QNGEKKLQEQ DNVQRIENPF KRNFKIYLIR YKVNILQFCY 
1981:	YIEKSSSELT DQEKSRKIVK TCNVYKQYIL LKDIENIYQT DVARIKNQES VNNRNKQFVD 
2041:	WELFKQAMRE SFERKFNANI AQQQIQAYQR QQDSLDSLKK DFSLSTIRLI AKYYKKLGGQ 
2101:	LELNGNLISE DVQIELLIKT LEKQQTNVFN LDNLKDFLKK CQEIFLNKEI YLIKLCRIFL 
2161:	QLKRPTQDEI DSLTEAKDED SKQFVRDKKE TYVKFQRAMA DGQLDILALE MLNQTDDDQQ 
2221:	KIEALSFLIH LLDYGNEYVQ KKFYKLLKEE HVKQKFLVFL RGFFLIDLDV RIKELELTNG 
2281:	DNTEYKLLCL KVLQLLQALC ENVNMEFQRF LVFQYDDDSY QANINIVNEV AGLLADLLEK 
2341:	GQRVFYKLQE IYRQALESLV EFSTGYVENK KELCKNARLF TLLNSILQKQ DLQNFSSLYK 
2401:	ENRMILKEKQ QMNQTLDEDI VLDGEGIATN EGKKKYSSYQ TLQSFIKLLL LLTQGRSDIQ 
2461:	SLEFILKTVD ITILIRISKS IYEERIKPKQ RNIILDNICD ESETGNHRHC TNSLCHFGLR 
2521:	TDEDNMLIQT GFNIFIICLK LSEHFTQDSQ LELFKFDEEQ EEQEDLLDLD DFQEEELQKK 
2581:	KTLSNQKILP INPGSKYDYN QDEGDGLLPG GDPKLENSSL KKIFLDVQND KSYQFDRTQR 
2641:	FFKFYRQFTG RIEIQNEFNQ LEKVFFQKPF VCNFITPNIK QHLIYEINRE TDEDRMLGLI 
2701:	EYSEFYQVQM RHSQYINNRK VMHFGAVYWR LLKDVSFLLC LIIVVLLIFM HDTVINSKIG 
2761:	SNTEAPEDQN VTSGESFVSY LNNIITIVQL VLNLIIVFFC AIERYPISIT YNRGQTNAKR 
2821:	VQILKKEAGF QISWLTMKYY SLIGYFESEF QEEKVNQSSI KKLILVIFFD FDNFYNICIF 
2881:	GLTVYAFFNP YIYAILLLDI VKRSEDLQNI IRSITSNGRN LAIFSFLGLI GLLIYAIIAF 
2941:	SNFDQMFDDE SGVYGQTFIL AVTSTINFGL RNGGGIGESL TKYPDAYDDP TLYWGRYFFD 
3001:	FTFFIIFNIL FIQIIFGIIL DTFGELRDER QALVKEIEGK CFICSQDKND IDTKGTKGWH 
3061:	YHIYLEHSVY HMLYYIIYIK NKDPNDCNAL EKYVNKCIQE KETKFFPFGR ALQIESQEGD 
3121:	QDQTEKQ