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1.A.3.2.7
Contractile vacuole complex calcium release channel (CRC)II; IP3Rn (Ladenburger et al. 2006).  Functions in osmoregulation by promoting expulsion of water and some ions including Ca2+.  Also functions in calcium homeostasis (Ladenburger et al. 2006; Docampo et al. 2013Docampo et al. 2013).

Accession Number:Q3SDX7
Protein Name:Inositol 1,4,5,-triphosphate receptor n-2
Length:2888
Molecular Weight:339535.00
Species:Paramecium tetraurelia [5888]
Number of TMSs:4
Substrate Ca2+

Cross database links:

External Searches:

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  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MEIIKIGSIV SISHLQDDDA LIGGDGFIKN AVILKGMSPL NKLDTKDFNI SYFSQMNIPN 
61:	CLFVVCPRTS NGKKVEVAKI FPQRKKKPFG SINDDVTDQK SEVTPVRSQI KSVTHSVQPL 
121:	LSEKQVRDNQ MNLFNEFKFN VDGFEKEKGN YVKYEEPIQL LHLASSKWLC SLLDEAKFEN 
181:	QNFKLALSDY TSDETLFKIV ATYKYQKEGD QIVYSQEIVR IMRMIPFLGK PTYLHCSGEI 
241:	PQKAIKEYRE NSEVKIQKRE INASLEESTS WKINLFAEEL PIDGDLVWIH HSETCSQLAV 
301:	DYERDLNRAK ISVFQTDLSE LSFDNYSGNA YSMWIIEGED YKKGGPYLYS NNYRLKHFHT 
361:	GLYLACVRVI PKEQEDIKID PYGKKKVIIP KSKKVPATFA LQVQPNKDSL FRFEPLKSVN 
421:	KDEIQSDFIQ IRSVTQGKYL DVINKFHQDE NTLKPVILNQ KNEHAVFKIF RANKQETQEV 
481:	LFLDSCTKQL RKYQFYINLL FKFEQNQMYQ SLSDDVELLK IKTKKLATAQ RCIQNLDDFL 
541:	RQKIYNSSPS QKYGFISPKR QKLLKDQHFF DVLLQILTST VTKQELEIWS NKKGNLKALE 
601:	QPSMTEKNQR KQQTISEKDK LELSNSKVEV CNMIFVLLQT SVINNTSNQL YLFERLPDYQ 
661:	HYCKYLPQTI NFLIEMVKSN EKILINLCNN LKIEFDYIKK QEIEDDLKNK VKVLINFYEK 
721:	DAGIQQDVSI PVKVHDRIIT RPINIIQYFF NLIIDDTAKN NEHYLRFLRH ICRYKNNAIS 
781:	INQENLFKLY KKYNKQTKLL QIETNNGCII DKEISFQYEL LQFFSEVSYG RNYLWQAELS 
841:	PLFEKDILIN QIWNPNQVEG NQIDDKLRSY WCRLSRTLYI DQQPFQYLIV PNFCRLYSPY 
901:	QDQLKNRNDE EIEKQFKLKK MFKYIKTKRS EVYEAIASRA SSDLLNDELV YNAADQILTM 
961:	LQLDIMPNKY YNKIIKYMSE MFIYDRKNLD YLNAAVKSYQ KTVTERKSKK SIVINQFGNV 
1021:	FSGMKDLIQL KQEDKEEIAE EEEDEEINLY DQPKLFLNPI MKGFMAMSNQ LEGLITLPKS 
1081:	QQEIEFKLKV CSILDHFLDR RQNFLISNIL LFFLKYQYTN DDLSDEDDDQ TIKAAPKIFN 
1141:	NNYKTLIPTI ARTGIDEIDE PEDTTQDFLQ MAVKKPPTFT NYFQQYNIKS EDEFQELDYY 
1201:	LSQAQKFDNN ERLSEDQLKE KQVASLLPYL MSTYFLVKDQ VLEERCLNVI MRVFNQREEL 
1261:	RENMKKLQIL FDDDNIKIYE FVEHLQKDLR VMVEKTEIWL TQFRAGYDVE ELDKCAQIIR 
1321:	QLTLCMRQGV QVNDRELVVE VVNKEINDSE KQSIMTFLKI HEIVINLIQN GMAHFISVLN 
1381:	DEFIKIERKE QLLLLFSNAF KFLICYCTNN KGNQLILYQY LEIYLQFIQY DVGQCKLLIE 
1441:	IFRDNPRLLN TGVKSLVQRL IEIIEREGRQ VKFVEILLNL ISIAGQYLLE NQILILNTFL 
1501:	PMRSLKETEQ RLLYAEGSQQ KDLRFYFDDQ FLEPEENLIK QLEAIDWKDC YRDEPFLYHS 
1561:	KILDLLLQTS LIDNTVREYN PSLMPTDNFN ISVFKLKKMI KPSYLLEILR LDDDMVSLKQ 
1621:	RLARMPTQFI KGQASQYQDE QFNKKKGYTA LKPIVCEFLR LVHIVSEKNN AQEGLLSQLS 
1681:	RQFIHFVEFE SKKLEFVAAG TDYQNCYVDY IIGQVIPLIL CYHQRVLSVQ QEDVKNALIE 
1741:	FSSQFAQALC STFYQKLTKY EQLEIISKLR EYYQNEYYEP AYRQEGEQSI LHLQHMQFQL 
1801:	EDGEDLQQPI EEQHVQSIQK KSQSKSKNLL SQFASLNLSL INKTSKHKRG DLTPIKLQEQ 
1861:	WKRFAEELFR SPKLEEQIDI EKEALADAII GIDKLIQEPC EIKPSLESIL KKFITFLQTA 
1921:	VLQQDNKGTI VILLKIMSKI IEKQDSDEKK EYYQKLFDNL GATRMVLNVI TDYSKLLSNE 
1981:	MLYYLISFIN VLLRNGNSQV QNTIFTFCQT QQKSEVMFQT FAKYLEIAAT SGRDKNEDKE 
2041:	EAEVQKQIVN CILKFFQNCT EGHYQDMQNY IRYQYNSRAS KDLINLVADL FKNYDRTKQN 
2101:	FSNLMCCLDT LNELVQGPCA ENQLAVADSK FFDVVQEMFP LRKGAVSQQK AVKSAATKRI 
2161:	SVLPSQSVSN LLTRGMKAQL QNKILVLVLS LLENREIKGK NSIIKRIMRV LPMNVLERHL 
2221:	SKIYKKWFNK YTGDYNMQAF ELLKIDAMDL DEESQEFKDC EIIIQNGFYI MFLICYYMES 
2281:	DEEIDSVFMG YNKQYLKSQI QQNSLFDPNS TLGQLFALGM ELYEMSLLKT QQMFNELNKT 
2341:	RKDDPEFILE QQKRKQEEKK KRLKKAFMFF RARTAHIEVV RDDQIELVFF PLLPFSKLNK 
2401:	DEKQSFQQTV DRSSAKSKVQ DLMEKSPELI QIMRHEEEMN RFYKQYKLIG FFANYIQLWK 
2461:	DLAFYLTLII NTMIIASFSH QSDPDRPKED VSSEALDEYV FFRKDEWTQA QTKELISALG 
2521:	YAMMVCSLFV VLFVLARIAP LIIKKALQRK PLLEGQGMIK LLINWLAKFF FVLFYCLQDF 
2581:	QLVYYLGYGA LSVIGTLVHP FFFCFHLTVI LIRYPTLSNV VRAVTMPWQQ LVLTLLLIII 
2641:	ITYIFTLIAF YALQDPFGLD CKEVSICFLQ IFDKNFKIPG GIGGDITNNN PSPTYEIFRY 
2701:	LYDQINNLLL VIIMVSIASG IIIDTFGQLR EDENKMNSDI KDKCFICGQE NIIFERSSDG 
2761:	SSGGFKNHIR QNHYMWNYLY YIAYLQWKDP QDYSGIESYV DKKIKDTDLS WIPFGRAREL 
2821:	DKGEDESEKQ AKQMEQSSSN IASLLTHSSD IIQALKEKKE KRKQHFTQQT QPTQYKEQIL 
2881:	SQQSMALL