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1.A.35.3.5
MIP family protein of 366 aas. Mg2+,Co2+ and the CorA-specific inhibitor (Co(III) hexamine chloride) bind in the loop at the same binding site. This site includes the glutamic acid residue from the conserved "MPEL" motif (Hu et al. 2009).

Accession Number:O50455
Protein Name:Magnesium transport protein CorA
Length:366
Molecular Weight:41501.00
Species:Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [83332]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Mg2+, Co2+

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MFPGFDALPE VLRPVARPQP PNAHPVAQPP AQALVDCGVY VCGQRLPGKY TYAAALREVR 
61:	EIELTGQEAF VWIGLHEPDE NQMQDVADVF GLHPLAVEDA VHAHQRPKLE RYDETLFLVL 
121:	KTVNYVPHES VVLAREIVKT GEIMIFVGKD FVVTVRHGEH GGLSEVRKRM DADPEHLRLG 
181:	PYAVMHAIAD YVVDHYLEVT NLMETDIDSI EEVAFAPGRK LDIEPIYLLK REVVELRRCV 
241:	NPLSTAFQRM QTESKDLISK EVRRYLRDVA DHQTEAADQI ASYDDMLNSL VQAALARVGM 
301:	QQNMDMRKIS AWAGIIAVPT MIAGIYGMNF HFMPELDSRW GYPTVIGGMV LICLFLYHVF 
361:	RNRNWL