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1.A.4.1.10
Trp-2 channel; controls nicotine-dependent behavior (Xiao and Xu 2009).  The TRPC orthologues TRP-1 and -2 genetically complement the loss of syndecan by suppressing neuronal guidance and locomotory defects related to increases in neuronal calcium levels. The widespread and conserved syndecan-TRPC axis therefore fine tunes cytoskeletal organization and cell behavior (Gopal et al. 2015).

Accession Number:G5EE02
Protein Name:Protein TRP-2, isoform a
Length:816
Molecular Weight:94781.00
Species:Caenorhabditis elegans [6239]
Number of TMSs:6
Substrate Ca2+

Cross database links:

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  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTSSEASEFR MIEDDDDVSN NVTWTESDNS RLREKQFLLS CERGDIGSVR KLLAGISTET 
61:	FNINCLDPLG RNALLIAIEN ENIEMIELLL DHNIETGDAI LYAIGEENVE AVEIIVEHLE 
121:	KMDKFDSERQ GVEITEHSAF TPDITPIVLA AHKDNYECIK LFLDKKGTVP HPHDVRCSCP 
181:	ECYVAREEDS LRLSRSRINA YRALTSPSLI CLSARDPILY AFELSWELKR LSFIENEFRT 
241:	DYEELSQKCQ KFCVHMLDQV RGSKELEVVL NHTTNAWHDV TSANYGNPEK LARLKLAIQL 
301:	SQKRFVAHPN CQQLLLDIWY EGVESVRCTN FIYKLIFYIL GMLSFPLFSL VYLLAPHSSM 
361:	GQFAKKPFIK FLSHSGSYIF FLILLIMASQ RMNVIDNILR TDDVDRKETR GPPPTIIECA 
421:	IFLWVLGLIW VEIKQLWECG LYNYCRNLWN ILDFITNSLY LCTTALRVVA YVQVEQEALR 
481:	ANSVHIARHL PRRDWDAWDP TLLSECFFAT ANIFSSLKLV HIFTVSPHLG PLKISLGRMV 
541:	IDIVKFFMVY ALVLFAFACG LNQLLWYYAS MRQNECNLYE QYKNEKSLSY KYEHLKESCD 
601:	DKYKSCSSIY HTAETLFWAL FGLVDLTHFR LKEDHFLSEW TGKTIFGSYC CCSIIVLLNM 
661:	LIAMMSNSYQ YISDQADIEW KFARSRLFLE YFDDTATLPP PFNIVPSPKS IYYCLHYLTK 
721:	KLCNCTKLQQ PSKQKSMRNQ KILRSVNDRE NNYRKTIIHA EQLQVELEQS ESESFTSFKI 
781:	QINRYYTSRC YPVTCVEQKI AASKTSPYEF RHLQSQ