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1.A.4.1.9
Trp-1 isoform channel; controls nicotne-dependent behavior (Xiao and Xu 2009). TRPC orthologues TRP-1 and -2 genetically complement the loss of syndecan by suppressing neuronal guidance and locomotory defects related to increases in neuronal calcium levels. The widespread and conserved syndecan-TRPC axis therefore fine tunes cytoskeletal organization and cell behavior (Gopal et al. 2015).

Accession Number:Q27GV1
Protein Name:Protein TRP-1, isoform b
Length:1047
Molecular Weight:120524.00
Species:Caenorhabditis elegans [6239]
Number of TMSs:9
Substrate Ca2+

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  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MLSAAGRRFS RCAPSPRPRR NYALANIPPP AAVHIRTNDM ISPEERRKSR VKSLKHAQLL 
61:	HGYYILSNNL FRFLEAAELG NKPTLQECLD YDGDRRLNVN CLDSMGRTAL EIAVDNENME 
121:	VVELLLQQPD IRIGNALLCA IREGVYRLVE VLVNHPNITR EMLGDGWSQA LDPSEAASAE 
181:	YSSDISPVIL AAQLNQFEIL QMLIRKDASI EKPHRHSCIC ETCDRERLND SLQYSLKRIN 
241:	TFRALASPAW MSLTSPDPIL SAFKLSWDLQ RLAFEEHEFK ETYLQLSEQC KQYSCDLLSQ 
301:	CRSSEEVIAI LNKDGNVNDD NIDVWASKLS LSRLKLAIKY EQKAFVSHPH CQQLLTSIWY 
361:	EGIPYRQRSG TWANFFLYAF LLFLWPIFCL MYILMPKSRL GRLVRSPFMK FFYYSVSFAT 
421:	FLGLLTWATF EDYRYEKGER GGMTRASDRG PPATWVESLV FTWVIGMLWS EIKQLWEEGF 
481:	KRYMRQWWNW LDFLMICLYL CTISIRLSAY YIFTYREDPY RYTVRTYWTS EEPMLVAEAL 
541:	FAVGNVFSFA RIIYLFQTNP YLGPLQISLG CMLVDVAKFC FIFVLIISSF SIGLAQLYWY 
601:	YDPNTDVCLP GATCKHSSNV FSSIADSYLT LLWSLFSITK PEDTDVVENH KITQWVGQGM 
661:	FIMYHCTSII VLLNMLIAMM SHSFQIINDH ADLEWKFHRT KLWMAHFDEG SSLPPPFNII 
721:	VTPKSLIYVM NCLFNTVRWL LGKYTYQKNR NRATIRRPGY SRKRNEMEKS GGHDDDSLKP 
781:	LTYADIITRL VARFIHQTKK DMKMDGVNED DLHEIKQDIS SLRYELRDDR RREIVRSSSH 
841:	IDAVKRDIMR TMSTTSRRPY GGSMRLPKTR PSVAEESEED DKSDETSSTD EEADETRSRK 
901:	SSVLYIPPVN STLPGIISEE APVKKSTKRR ASEADSKLPD RPLSDTYTSS FTPKLLPVFA 
961:	QPPHSALRKT DTSMSFPING TALDTSIVKP PRGVLRASQE NLPAVELIET LKKEMNEKLD 
1021:	RLISGISENV KSPSPASHSH VGFNVEK