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1.A.4.5.10
TrpCC family member, Gon2. Required for initiation and continuation of postembryonic mitotic cell division of gonadal cells Z1 and Z4. Zygotic expression is necessary for hermaphrodite fertility. Probably a cation channel that functions together with Gem1 (TC#2.A.1.13.22) (Kemp et al. 2009).

Accession Number:Q93971
Protein Name:Transient receptor potential channel
Length:2032
Molecular Weight:229063.00
Species:Caenorhabditis elegans [6239]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate cations

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  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MMSDDMLDEN DENFACQDVD EIIIYVPEFA GYREVNIDTA VSVCPTPIQQ ARRESSCRNL 
61:	EMRRRFEKLR REKKEEKKLL ADDEKDFDED DDVFEDGEGL QMRTFQPNAS IRDENGSMPS 
121:	LLPRTAPIKK TRKHRRRRSG SFTGGVYPRK GHRNRSLLGH AIPPPNVHSA DWRDMLAITD 
181:	NKDDKLMKTL GVTRYLQSKG GDQVPPTSTT TGGAGGDGNA VPTTSQAQAQ TFNSGRQTTG 
241:	MSSGDRLNED VSATANSAQL VLPTPLFNQM RFTESNMSLN RHNWVRETFT RRECSRFIAS 
301:	SRDLHKCGCG RTRDAHRNIP ELTSEFLRQK RSVAALEQQR SISNVNDDIN TQNMYTKRGA 
361:	NEKWSLRKHT VSLATNAFGQ VEFQGGPHPY KAQYVRVNFD TEPAYIMSLF EHVWQISPPR 
421:	LIITVHGGTS NFDLQPKLAR VFRKGLLKAA STTGAWIITS GCDTGVVKHV AAALEGAQSA 
481:	QRNKIVCIGI APWGLLKKRE DFIGQDKTVP YYPSSSKGRF TGLNNRHSYF LLVDNGTVGR 
541:	YGAEVILRKR LEMYISQKQK IFGGTRSVPV VCVVLEGGSC TIRSVLDYVT NVPRVPVVVC 
601:	DGSGRAADLL AFAHQNVTED GLLPDDIRRQ VLLLVETTFG CSEAAAHRLL HELTVCAQHK 
661:	NLLTIFRLGE QGEHDVDHAI LTALLKGQNL SAADQLALAL AWNRVDIARS DVFAMGHEWP 
721:	QAALHNAMME ALIHDRVDFV RLLLEQGINM QKFLTISRLD ELYNTDKGPP NTLFYIVRDV 
781:	VRVRQGYRFK LPDIGLVIEK LMGNSYQCSY TTSEFRDKYK QRMKRVKHAQ KKAMGVFSSR 
841:	PSRTGSGIAS RQSTEGMGGV GGGSSVAGVF GNSFGNQDPP LDPHVNRSAL SGSRALSNHI 
901:	LWRSAFRGNF PANPMRPPNL GDSRDCGSEF DEELSLTSAS DGSQTEPDFR YPYSELMIWA 
961:	VLTKRQDMAM CMWQHGEEAM AKALVACRLY KSLATEAAED YLEVEICEEL KKYAEEFRIL 
1021:	SLELLDHCYH VDDAQTLQLL TYELSNWSNE TCLALAVIVN NKHFLAHPCC QILLADLWHG 
1081:	GLRMRTHSNI KVVLGLICPP FIQMLEFKTR EELLNQPQTA AEHQNDMNYS SSSSSSSSSS 
1141:	SSSSSSDSSS FEDDDDENNA HNHDQKRTRK TSQGSAQSLN ITSLFHSRRR KAKKNEKCDR 
1201:	ETDASACEAG NRQIQNGGLT AEYGTFGESN GVSPPPPYMR ANSRSRYNNR SDMSKTSSVI 
1261:	FGSDPNLSKL QKSNITSTDR PNPMEQFQGT RKIKMRRRFY EFYSAPISTF WSWTISFILF 
1321:	ITFFTYTLLV KTPPRPTVIE YILIAYVAAF GLEQVRKIIM SDAKPFYEKI RTYVCSFWNC 
1381:	VTILAIIFYI VGFFMRCFGS VAYGRVILAC DSVLWTMKLL DYMSVHPKLG PYVTMAGKMI 
1441:	QNMSYIIVML VVTLLSFGLA RQSITYPDET WHWILVRNIF LKPYFMLYGE VYADEIDTCG 
1501:	DEAWDQHLEN GGPVILGNGT TGLSCVPGYW IPPLLMTFFL LIANILLMSM LIAIFNHIFD 
1561:	ATDEMSQQIW LFQRYKQVME YESTPFLPPP LTPLYHGVLI LQFVRTRLSC SKSQERNPMF 
1621:	DFSLKLFLDN DQIEKLHDFE EDCMEDLARQ KLNEKNTSNE QRILRADIRT DQILNRLIDL 
1681:	QAKESMGRDV INDVESRLAS VEKAQNEILE CVRALLNQNN APTAIGRCFS PSPDPLVETA 
1741:	NGTPGPLLLK LPGTDPILEE KDHDSGENSN SLPPGRIRRN RTATICGGYV SEERNMMLLS 
1801:	PKPSDVSGIP QQRLMSVTSM DPLPLPLAKL STMSIRRRHE EYTSITDSIA IRHPERRIRN 
1861:	NRSNSSEHDE SAVDSEGGGN VTSSPRKRST RDLRMTPSSQ VEESTSRDQI FEIDHPEHEE 
1921:	DEAQADCELT DVITEEEDEE EDDEEDDSHE RHHIHPRRKS SRQNRQPSHT LETDLSEGEE 
1981:	VDPLDVLKMK ELPIIHQILN EEEQAGAPHS TPVIASPSSS RADLTSQKCS DV