TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


1.A.4.6.7
TRP ankyrin 1 (TRPA1 of 1188 aas).  It is a homotetrameric, non-selective, cation channel with multiple ankyrin repeats at the N-terminus.  The systems from insects to birds are heat activatable, and this activation is dependent on an extracellular Ca2+ binding site near the vestibule surface. Neutralization of acidic amino acids by extracellular Ca2+ seems to be important for heat-evoked activation (Kurganov et al. 2017).

Accession Number:G1KQ06
Protein Name:Uncharacterized protein
Length:1188
Molecular Weight:133994.00
Species:Anolis carolinensis (Green anole) [28377]
Number of TMSs:7
Substrate cations

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MMVISFPLVL PQEPLESREA SFPSLPFPRR SFSSPPPPQA DAGSLFGCGG APGREGGRQG 
61:	RKRGLSMASP LTRCLLLVPP AGSQAARSPA MKRSLRKWLQ SGEKKARTSY EGVVCEADAA 
121:	SLASQDVFKV ISDGSTSRLR SFIKKNREGL KKLDDLNATP LHHAAGQGQL ELMQMIIDSS 
181:	SEALNVTDTS GNTPLHWATK KNQIESVKLL LSRGANPNIL NSNMMAPLHL AVQSLRNELV 
241:	KIFVEHTTTD INLEGENGNT PITIACYKDN SEALKLLIEN GAKICKGNSM GWMPVHAAAF 
301:	SGAKACMEIL IKRGEETGYS PENHINFTNN GKCTALHLAV QSGDLEMIKM CIEYGAQIDL 
361:	KQNDKCTALH FAATQGATEI LKLMMSSYTG DEPIIDALDE NKETLLHRVA LFDHYELAEY 
421:	LITMGAKIDS VDIEGRTPLL LATSCASWKI VNLLLSKGAN VELKDHLGRN FLHLTVLHPG 
481:	GLKHLNEQFL KMKHIKELVT DEDNDGCTPL HYACRQGVPL SVNSLLELDV SIYSKSRDKK 
541:	SPLHFAASYG RINTCQRLLR DMVDTRLLNE GDKKGMTPLH LAAQNGHEKV VQFLLRKGAL 
601:	FLCDYKGWTA LHHAAFGGYT RTMQIILNTN VKCTDKVDEE GNTALHLAAK EGHPKAVRLL 
661:	LDDNAKILLN KSDASFLHEA IHNGRKEVVN ATILHKRWEE SMTTFSHYSS ANKCAILEMV 
721:	EYLPECLKLV LDNCMIESCE EKTCRDFHIE YNFRYLQCPL KLTKQFKEGD EIMYEPLHNL 
781:	NAMVRHNRVE LLSHPVCTEY LLMKWMAYGF KAHLMNLAVY SLGLIPLTLL IVHIERPEPP 
841:	YNATVKSGPF GKKNSYFIKV CMCLVFIMSV FGICKEIVQL FQQKLRYLLD YSNLLDWIIY 
901:	TTSITFVSSL FINLPANLQW ECGATAIFLS WMNFLLYLQR FENFGIYVVM FWEILRTLIR 
961:	IAIVFFFLML AFGLSFHVLL GSQEAYGTPY LSVMQTFAMM LGDINYHDAF LEPMLTNKLP 
1021:	YPLLSYIILI VFTLLIPILL MNLLIGLAVG DIAEVQKFAV LKRIAMQVNL HTNLEKKLPY 
1081:	WFLSRVDQES ITVYPNRPRY CGFMSVFQYC FGCDDRASNV PSADTSLELE VLKQKYRLKD 
1141:	IATLMEKQHD LLKLVVQKME IISEAEDEDT NDLFQHKFRK QQLEHKNN