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1.A.4.9.1
Flavin carrier protein 1 (Bypass of PAM1 protein 1) (FAD transporter 1) (Heme utilization factor 1) (TRP-like ion channel protein FLC1)

Accession Number:Q08967
Protein Name:Flavin carrier protein 1
Length:793
Molecular Weight:89291.00
Species:Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Endoplasmic reticulum membrane1 / Multi-pass membrane protein2
Substrate ions

Cross database links:

Genevestigator: Q08967
eggNOG: NOG74375
HEGENOM: HOG000168830
DIP: DIP-3965N
Entrez Gene ID: 855880   
Pfam: PF06011   
KEGG: sce:YPL221W   

Gene Ontology

GO:0005935 C:cellular bud neck
GO:0005783 C:endoplasmic reticulum
GO:0005789 C:endoplasmic reticulum membrane
GO:0000324 C:fungal-type vacuole
GO:0016021 C:integral to membrane
GO:0015230 F:FAD transmembrane transporter activity
GO:0009272 P:fungal-type cell wall biogenesis
GO:0006457 P:protein folding

References (6)

[1] “The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.”  Bussey H.et.al.   9169875
[2] “Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.”  Gruhler A.et.al.   15665377
[3] “A screen for genes of heme uptake identifies the FLC family required for import of FAD into the endoplasmic reticulum.”  Protchenko O.et.al.   16717099
[4] “A global topology map of the Saccharomyces cerevisiae membrane proteome.”  Kim H.et.al.   16847258
[5] “Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.”  Li X.et.al.   17330950
[6] “A multidimensional chromatography technology for in-depth phosphoproteome analysis.”  Albuquerque C.P.et.al.   18407956

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MQVLVTLWCL ICTCLVLPVA AKKRTLTASS LVTCMENSQL SANSFDVSFS PDDRSLHYDL 
61:	DMTTQIDSYI YAYVDVYAYG FKIITENFDV CSMGWKQFCP VHPGNIQIDS IEYIAQKYVK 
121:	MIPGIAYQVP DIDAYVRLNI YNNVSENLAC IQVFFSNGKT VSQIGVKWVT AVIAGIGLLT 
181:	SAVLSTFGNS TAASHISANT MSLFLYFQSV AVVAMQHVDS VPPIAAAWSE NLAWSMGLIR 
241:	ITFMQKIFRW YVEATGGSAS LYLTATTMSV LTQRGLDYLK NTSVYKRAEN VLYGNSNTLI 
301:	FRGIKRMGYR MKIENTAIVC TGFTFFVLCG YFLAGFIMAC KYSIELCIRC GWMRSDRFYQ 
361:	FRKNWRSVLK GSLLRYIYIG FTQLTILSFW EFTERDSAGV IVIACLFIVL SCGLMAWAAY 
421:	RTIFFASKSV EMYNNPAALL YGDEYVLNKY GFFYTMFNAK HYWWNALLTT YILVKALFVG 
481:	FAQASGKTQA LAIFIIDLAY FVAIIRYKPY LDRPTNIVNI FICTVTLVNS FLFMFFSNLF 
541:	NQKYAVSAIM GWVFFIMNAA FSLLLLLMIL AFTTIILFSK NPDSRFKPAK DDRASFQKHA 
601:	IPHEGALNKS VANELMALGN VAKDHTENWE YELKSQEGKS EDNLFGVEYD DEKTGTNSEN 
661:	AESSSKETTR PTFSEKVLRS LSIKRNKSKL GSFKRSAPDK ITQQEVSPDR ASSSPNSKSY 
721:	PGVSHTRQES EANNGLINAY EDEQFSLMEP SILEDAASST QMHAMPARDL SLSSVANAQD 
781:	VTKKANILDP DYL