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1.A.43.2.4
Plasma membrane fluoride ( > chloride) export channel of 375 aas and 8 TMSs, FEX1 (Li et al. 2013). The two homologous 4 TMS domains are functionally assymetric (Smith et al. 2015).  There are two very similar fex genes in S. cerevisiae, the other having TC# 1.A.43.2.5. Fex1 is consitutively synthesized (Smith et al. 2015).

Accession Number:Q08913
Protein Name:UPF0695 membrane protein YOR390W
Length:375
Molecular Weight:41985.00
Species:Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292]
Number of TMSs:8
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Fl-, Cl-

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MIFNPVISNH KLSHYIHVFC TFTTFCILGT ETRQAITALS TYTPAFVTAP TVLWSNCSSC 
61:	MLMGIMQSLN AYTWMKDHQV LFLGVTTGYC GALSSFSSML LEMFEHSTNL TNGNIANHTK 
121:	LPNRAYGIME FLSVLLVHLM VSMGSLIFGR QLGKEVIVAY GSSSFSKPYT PPSDTVKENA 
181:	GDVDTQEMEK NILEFKFKTP APFFKKFFDI VDKLAYALAF PLIILFVVLC AYYENYSRGK 
241:	WTLPCLFGIF AGFLRYWLAE MFNKTNKKFP LGTFLANVFA TLLIGIFTMV QRGKKHFSTD 
301:	VPIVNSLNSC HIVSALISGF CGTLSTISTF INEGYKLSFI NMLIYYTVSI AISYCLLVIT 
361:	LGSYAWTRGL TNPIC