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1.A.46.1.3
Bestrophin family anion channel, YxaK (Protein R13.3) (Sun et al., 2002)

Accession Number:Q21973
Protein Name:YxaK
Length:525
Molecular Weight:60485.00
Species:Caenorhabditis elegans [6239]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate anions

Cross database links:

eggNOG: KOG3547
HEGENOM: HBG385747
RefSeq: NP_502007.2   
Entrez Gene ID: 177975   
Pfam: PF01062   
KEGG: cel:R13.3   

References (2)

[1] “The vitelliform macular dystrophy protein defines a new family of chloride channels.”  Sun H.et.al.   11904445
[2] “Genome sequence of the nematode C. elegans: a platform for investigating biology.”  The C. elegans sequencing consortiumet.al.   9851916

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTVNYNLDVS SASIFSFLRL QLRWKGSIWK YLLKELFMFI IAFITVSSVY RSNLIIGEKT 
61:	RKIWDNFAAL FDQNMDFIPL TFMLGFFVTI IVRRWNDIFA NLGWVENTAI TVANYIRGTD 
121:	DRTRMIRRNV IRYMVLAQVL VFRDCSIQVR KRFPTMESIV SAGFMLEHEK EALDNVQCGK 
181:	LQKYFVPIQW STGLLVDARA EGKIAADLLM NEIGKHIIEF RKMLALLSNY DWVPIPLAYP 
241:	QVVFLAVRSY FFMALIARQS VLLDGKEPEQ PSILYPTVPF VMSILQFIFV VGWMKVAESM 
301:	INPLGEDDDD FECNYLLDRN LMIGLCIVDD NYNRTPSVEK DAFWCADVEP LYSVETAMIP 
361:	KNPQIGSAAN YDVKVDEEEV MMMPHMDDVD LFDFESTNNL IPRKTFSVIS IQRPFGSRAS 
421:	LASRKRSMMF DQLRGRIAKK QHRSNMFQNS VSQASLHYFE SQAPSEINLS TLEMTAPKRK 
481:	SSTGKLGSMN VAEEQHKLSA EVLPIVIEED EERSKMLEKD KNKNA