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1.A.46.2.7
Chloroplast bestrophin homologue of 410 aas and 4 or 5 TMSs, VCCN1. Plants adjust photosynthetic light utilization by controlling electron transport and photoprotective mechanisms, and this involves the proton motive force (PMF) across the thylakoid membrane. VCCN1 is a voltage-dependent Cl- channel which localizes to the thylakoid membrane and fine-tunes the PMF by anion influx into the lumen during illumination, adjusting electron transport and photoprotective mechanisms (Herdean et al. 2016). The activity of AtVCCN1 accelerates the activation of photoprotective mechanisms on sudden shifts to high light. Thus, AtVCCN1 acts as an early component in the rapid adjustment of photosynthesis in variable light intensities.

Accession Number:Q9M2D2
Protein Name:UPF0187 protein At3g61320, chloroplastic
Length:410
Molecular Weight:46539.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Plastid1 / Multi-pass membrane protein2
Substrate anions

Cross database links:

Genevestigator: Q9M2D2
HEGENOM: HBG595462
Entrez Gene ID: 825304   
Pfam: PF01062   
KEGG: ath:AT3G61320   

Gene Ontology

GO:0031969 C:chloroplast membrane
GO:0016021 C:integral to membrane

References (2)

[1] “Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.”  Salanoubat M.et.al.   11130713
[2] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172

External Searches:

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  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MYQSMNLSVS SNFTHRSLLE SRFPIFSTGF RKSVNLKPPR VSSGPESNDS GHETLTDKLI 
61:	HLLRAVPDWA DEIKERGMQQ KRSLYTHEKW VEHRSSLRHV RHLLSSFSSR VILSLIPPVF 
121:	FFTSVAVVIA SYNSAVALDW LPGIFPILRS SSLPYQLTAP ALALLLVFRT EASYSRYEEG 
181:	RKAWVGIIAG TNDLARQVIC SVDSSGDELI IKDLLLRYIA AFPVALKCHV IYGSDIARDL 
241:	RNLIEADDLS LILQAKHRPR CVIEFISQSI QLLKLDDAKR DLLESKMLHL HEGIGVCEQL 
301:	MGIPIPLSYT RLTSRFLVFW HLTLPIILWD ECHWIVVPAT FISAASLFCI EEVGVLIEEP 
361:	FPMLALDELC DLVHSNIQEA VKSEKVIRNR IIAKIKLHEF KHSSNGRHRS