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1.A.48.1.5
Protein tweety-2 (Dttyh2)

Accession Number:Q9W5A5
Protein Name:Protein tweety-2
Length:655
Molecular Weight:71406.00
Species:Drosophila melanogaster (Fruit fly) [7227]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate anions

Cross database links:

eggNOG: NOG250159
Entrez Gene ID: 31071   
Pfam: PF04906   
KEGG: dme:Dmel_CG3638   

Gene Ontology

GO:0034707 C:chloride channel complex
GO:0005886 C:plasma membrane
GO:0005254 F:chloride channel activity
GO:0002121 P:inter-male aggressive behavior
GO:0016319 P:mushroom body development
GO:0006911 P:phagocytosis, engulfment

References (5)

[1] “The genome sequence of Drosophila melanogaster.”  Adams M.D.et.al.   10731132
[2] “Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.”  Misra S.et.al.   12537572
[3] “From sequence to chromosome: the tip of the X chromosome of D. melanogaster.”  Benos P.V.et.al.   10731137
[4] “The Drosophila tweety family: molecular candidates for large-conductance Ca2+-activated Cl- channels.”  Suzuki M.et.al.   16219661
[5] “Phosphoproteome analysis of Drosophila melanogaster embryos.”  Zhai B.et.al.   18327897

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MEQPSILVKI LHSIPHVNYT FRRVNDTFNP DSDVYLEPTN NKLQCQQKGI ELQSLVILAS 
61:	IPAGLLIGSL LGLLLYLLTR CCDRRQRKPS AQRCQSCSLV IITLMTCAAI GLGLYGNDDF 
121:	HNGLLQAFGS GKSVEGLVLT LKRQTESIKH DLETRMAGHK VEQLVEKPHY NQTVVMLLIE 
181:	TSRLVTENTS RAVASLDSMV HYFMKAKGSE NDTSLMGLLQ LGEFYESIRW PATLAFLTVL 
241:	LLLCTVLVIG VARRSRCTLI FFSVSGLFCI IICWLLAGVY LASSVAAGDF CMRPHDYMCR 
301:	QVGMRSPYVD FLNCGTPRNR FILRLNESRD LVDRARESVE HMQRMSQETY PHIDIQRTLN 
361:	AMDNDLEITL RNLTTLSATL DRRTIDMHYE EALRGLCGGG LLGLSLMMVA GLLTSFLLTI 
421:	LVYADSHAWI YLTKRPTLDA DKSETAPLFP ASNAPSASIS PTAPLSTGTI NRTLLHHQQA 
481:	SSGGGSGTLP GSGGGAGAGG GVGANGHNGV GPYRNGSAGL RQGLASPSSQ SSHTSSTATY 
541:	NNGTTSYHNS HQQHNNHLYS NHYSHSNNHY NNTQHRTNPA AGAVAAAVGV VSSGQRSPSP 
601:	PPVYDLVHGT RSGHHTLGRL PSHHQQSATY LPGPNNGKYA TLSKQCKTLE SNDFY