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1.A.56.1.1
Plasma membrane copper uptake transporter; takes up Cu2+ into the cytoplasm (Andrés-Colás et al. 2010).  Met-rich motifs in the N-terminal region, an MXXXM motif in TMS-2, and a GXXXG motif in TMS-3 could be essential for Cu transport since they are highly conserved in all analyzed species (Vatansever et al. 2016).

Accession Number:Q39065
Protein Name:COPT aka CopT1 aka AT5G59030 aka K18B18.2 aka K18B18.10
Length:170
Molecular Weight:18399.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate Cu2+

Cross database links:

Genevestigator: Q39065
eggNOG: KOG3386
HEGENOM: HBG749299
RefSeq: NP_200711.1   
Entrez Gene ID: 836020   
Pfam: PF04145   
KEGG: ath:AT5G59030   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005375 F:copper ion transmembrane transporter activity
GO:0006825 P:copper ion transport
GO:0048235 P:pollen sperm cell differentiation
GO:0048364 P:root development

References (3)

[1] “Molecular characterization of a putative Arabidopsis thaliana copper transporter and its yeast homologue.”  Kampfenkel K.K.K.et.al.   7499355
[2] “Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence features of the regions of 3,076,755 bp covered by sixty P1 and TAC clones.”  Sato S.et.al.   10718197
[3] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MDHDHMHGMP RPSSSSSSSP SSMMNNGSMN EGGGHHHMKM MMHMTFFWGK NTEVLFSGWP 
61:	GTSSGMYALC LIFVFFLAVL TEWLAHSSLL RGSTGDSANR AAGLIQTAVY TLRIGLAYLV 
121:	MLAVMSFNAG VFLVALAGHA VGFMLFGSQT FRNTSDDRKT NYVPPSGCAC