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1.A.56.1.8
The plasma membrane copper import transporter, Ctr1A (3 isoforms in Drosophila, Ctr1A, 1B and 1C; Ctr1A but not Ctr1B is required for development) (Turski and Thiele, 2007)

Accession Number:Q9W3X9
Protein Name:CG3977-PA
Length:231
Molecular Weight:25647.00
Species:Drosophila melanogaster (Fruit fly) [7227]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Endoplasmic reticulum membrane1 / Multi-pass membrane protein2
Substrate Cu+

Cross database links:

RefSeq: NP_572336.2   
Entrez Gene ID: 31601   
Pfam: PF04145   
KEGG: dme:Dmel_CG3977   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015088 F:copper uptake transmembrane transporter act...
GO:0005515 F:protein binding
GO:0006878 P:cellular copper ion homeostasis
GO:0015679 P:plasma membrane copper ion transport
GO:0002027 P:regulation of heart rate

References (2)

[1] “Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.”  Misra S.et.al.   12537572
[2] “The genome sequence of Drosophila melanogaster.”  Adams M.D.et.al.   10731132

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MDHAHHSAPG VDHSMHHDHV GMHHDHSGIP AATASPMDAA SMFDLIPDTS DLQASHAGHA 
61:	AHGAHNHGGG SGTGMEHMMP MAFHFGYNET ILFSWWHIET VAGLIGSMIA IFLLALMYEG 
121:	LKYYREYLFW KTYNLLEYRP VTGPQRNPEA PRIPSPAAAA PSPVQPSMLS INHLLQTLLH 
181:	VLQVTLSFLL MLIFMTYNVW LCLMVVLGAA VGYFLFCWKK SVIVDVTEHC H