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1.A.6.1.11
(Bile) acid-sensitive ion channel, BASIC (ASIC, ACCN5, HINAC), of 505 aas. Cation channel that gives rise to very low constitutive currents in the absence of activation. The activated channel exhibits selectivity for sodium, and is inhibited by amiloride (Schaefer et al. 2000).  A cytoplasmic amphipathic α-helix controls activity (Schmidt et al. 2016).

Accession Number:Q9NY37
Protein Name:Acid-sensing ion channel 5
Length:505
Molecular Weight:57464.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate ions, Na+

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MEQTEKSKVY AENGLLEKIK LCLSKKPLPS PTERKKFDHD FAISTSFHGI HNIVQNRSKI 
61:	RRVLWLVVVL GSVSLVTWQI YIRLLNYFTW PTTTSIEVQY VEKMEFPAVT FCNLNRFQTD 
121:	AVAKFGVIFF LWHIVSKVLH LQEITANSTG SREATDFAAS HQNFSIVEFI RNKGFYLNNS 
181:	TLLDCEFFGK PCSPKDFAHV FTEYGNCFTF NHGETLQAKR KVSVSGRGLS LLFNVNQEAF 
241:	TDNPALGFVD AGIIFVIHSP KKVPQFDGLG LLSPVGMHAR VTIRQVKTVH QEYPWGECNP 
301:	NIKLQNFSSY STSGCLKECK AQHIKKQCGC VPFLLPGYGI ECDLQKYFSC VSPVLDHIEF 
361:	KDLCTVGTHN SSCPVSCEEI EYPATISYSS FPSQKALKYL SKKLNQSRKY IRENLVKIEI 
421:	NYSDLNYKIT QQQKAVSVSE LLADLGGQLG LFCGASLITI IEIIEYLFTN FYWICIFFLL 
481:	KISEMTQWTP PPQNHLGNKN RIEEC