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1.A.6.1.4
ACD-1 (degenerin-like glial acid-sensitive channel) is constitutively open and impermeable to Ca2+, yet is required with neuronal DEG/ENaC channel, DEG-1 (1.A.6.2.1) for acid avoidance and chemotaxis to the amino acid lysine (Wang et al. 2008).

Accession Number:P91102
Protein Name:Putative uncharacterized protein
Length:635
Molecular Weight:71604.00
Species:Caenorhabditis elegans [6239]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Secreted1
Substrate Ca2+

Cross database links:

eggNOG: meNOG13949
HEGENOM: HBG386677
RefSeq: NP_491295.2   
Entrez Gene ID: 182852   
Pfam: PF00858   
KEGG: cel:C24G7.2   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005272 F:sodium channel activity
GO:0006814 P:sodium ion transport

References (1)

[1] “Genome sequence of the nematode C. elegans: a platform for investigating biology.”  The C. elegans sequencing consortiumet.al.   9851916

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MEPTLSPNYR NEAFEHDDSY LVNFVAGSSS GESSTPPPSF VPKCNFRYNQ SRSQMIIEVP 
61:	VAQLKKLRKL EGTVSIKRET QHFCETTTMH GPKRIFQGKR WATLFWLIMV SCSLGLLITQ 
121:	VFILASEYLS KPTVSDVSFL INEDGMDFPL ITICNLNPIR KTYVNEINKT GEVSPPMINY 
181:	MMKWFTEIPT LIGGADRPTL HEGNEELKLY MKNHLNFTVD SFFMNSGFSC PDIFKLCSFQ 
241:	GEIFDCCTLS TEVLTPLGKC FTLDLSSSTK ASMHKQTEPG IQAGLAITLD AHLEEQFDGS 
301:	NGMDALFTNS FVNGFRYFVH PPNTIPHLSS DEFTVSPNTV AFSAISSDRY VLLPTHQWGN 
361:	CTENFPDGIQ SNLSYSSGNC LSLCKAKFYM ENCGCTPALY NIENNLKECT PYETTTCLDN 
421:	ILAKPNKETG KIEFQTPNCK ACAQQCNSLV YRAYNSYGSQ FSAGAFHYLK SINPEWTDGH 
481:	MRANFQMINI FYRDMSYTEY NQVQDASVTQ LLSDIGGNMG MFLGMSVITI TEICLFFSKM 
541:	FWLGFSKKRR DYMYSKRVNE KTHEREVCET VEKMKAIASQ GNLSSIAGTT SAKNSIPNDN 
601:	VEFRINLKDL ADQLDSDSGY SQNQPDSRNA SFQKY