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1.A.6.3.1
Peptide neurotransmitter-gated ionotropic receptor

Accession Number:Q25011
Protein Name:FANA
Length:625
Molecular Weight:71351.00
Species:Helix aspersa (Brown garden snail) [6535]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate ions

Cross database links:

Pfam: PF00858   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005272 F:sodium channel activity
GO:0006814 P:sodium ion transport

References (1)

[1] “Cloning of the amiloride-sensitive FMRFamide peptide-gated sodium channel.”  Lingueglia E.et.al.   7501021

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MKYTSAATKP GVFPEHHQHA MMRNRYHPHH CNYSDNRSAI DIIAELGSES NAHGLAKIVT 
61:	SRDTKRKVIW ALLVIAGFTA ATLQLSLLVR KYLQFQVVEL SEIKDSMPVQ YPSVSICNIE 
121:	PISLRTIRRM YFNNESQNLI TWLRFIQKFR FEQDSFMNSI RAFYENLGQD AKKLSHNLED 
181:	MLMHCRFNRE LCHVSNFSTF FDGNYFNCFT FNSGQRLQMH ATGPENGLSL IFSVEKDDPL 
241:	PGTYGVYNFD NNILHSAGVR VVVHAPGSMP SPVDHGIDIP PGYSSSVGLK AILHTRLPYP 
301:	YGNCTNDMLN GIKQYKYTFF ACLQLCKQRL IIQRCGCKSS ALPEVPSYNA TFCGVIKDWQ 
361:	EINRNHSNED HNQSEEDRAF IPTPYLACEE REQKNLNNDR TYELSCGCFQ PCSETSYLKS 
421:	VSLSYWPLEF YQLSAVERFF KQERQAGQNH FMKTAYEYLE KLAHPSQKHL ARNDSHMDDI 
481:	LSKSYSLSEK EMAKEASDLI RQNMLRLNIY LEDLSVVEYR QLPAYGLADL FADIGGTLGL 
541:	WMGISVLTIM ELIELVIRLT GLVFNSEKGL PRGPTTVNNN NGSNNHSQST SQHQLYNGYM 
601:	DHDSHYSDSA GASVFDFRRG VESPV