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1.A.64.1.1
Channel-forming Plasmolipin (Fischer and Sapirstein, 1994)

Accession Number:P47987
Protein Name:Plasmolipin
Length:182
Molecular Weight:19834.00
Species:Rattus norvegicus (Rat). [10116]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate ions

Cross database links:

Genevestigator: P47987
eggNOG: roNOG15822
RefSeq: NP_071978.1   
Entrez Gene ID: 64364   
Pfam: PF01284   
KEGG: rno:64364   

Gene Ontology

GO:0043218 C:compact myelin
GO:0016021 C:integral to membrane
GO:0045121 C:membrane raft
GO:0005216 F:ion channel activity
GO:0006811 P:ion transport
GO:0042552 P:myelination
GO:0009611 P:response to wounding

References (3)

[1] “Molecular cloning of plasmolipin. Characterization of a novel proteolipid restricted to brain and kidney.”  Fischer I.et.al.   7929173
[2] “Full-lenth cloning, expression and cellular localization of rat plasmolipin mRNA, a proteolipid of PNS and CNS.”  Gillen C.et.al.   8714710
[3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MAEFPSKVST RTSSPAQGVG ASVSAMRPDL GFVRSALGVL ALLQLVLGLL VWALIADTPY 
61:	HLYPAYGWVM FVAVFLWLVT IVFFIIYLFQ LHMKLYMVPW PLVLLVFFVA ATVLYITAFV 
121:	ACAAAVDLTS LRGSRPYNQR SAASFFACLV MIAYGLSAFF SFQAWRGVGS NAATSQMAGG 
181:	YS