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1.A.64.5.2
Proteolipid protein 2 (Differentiation-dependent protein A4) (Intestinal membrane A4 protein)

Accession Number:Q04941
Protein Name:Proteolipid protein 2
Length:152
Molecular Weight:16691.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate ions

Cross database links:

Genevestigator: Q04941
eggNOG: NOG296424
HEGENOM: HOG000293179
Entrez Gene ID: 5355   
Pfam: PF01284   
KEGG: hsa:5355   

Gene Ontology

GO:0005789 C:endoplasmic reticulum membrane
GO:0016021 C:integral to membrane
GO:0005624 C:membrane fraction
GO:0005886 C:plasma membrane
GO:0015075 F:ion transmembrane transporter activity
GO:0006935 P:chemotaxis
GO:0019221 P:cytokine-mediated signaling pathway

References (6)

[1] “Isolation and characterization of a differentiation-dependent gene in the human colonic cell line HT29-18.”  Oliva M.M.et.al.   8470895
[2] “Sequence-based exon prediction around the synaptophysin locus reveals a gene-rich area containing novel genes in human proximal Xp.”  Fisher S.E.et.al.   9344658
[3] “Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.”  Kimura K.et.al.   16344560
[4] “The DNA sequence of the human X chromosome.”  Ross M.T.et.al.   15772651
[5] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[6] “Initial characterization of the human central proteome.”  Burkard T.R.et.al.   21269460

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MADSERLSAP GCWAACTNFS RTRKGILLFA EIILCLVILI CFSASTPGYS SLSVIEMILA 
61:	AIFFVVYMCD LHTKIPFINW PWSDFFRTLI AAILYLITSI VVLVERGNHS KIVAGVLGLI 
121:	ATCLFGYDAY VTFPVRQPRH TAAPTDPADG PV