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1.A.75.1.3
Piezo mechanosensitive ion channel (Kim et al., 2012)

Accession Number:Q9VLS3
Protein Name:CG8486, isoform D
Length:2760
Molecular Weight:312529.00
Species:Drosophila melanogaster (Fruit fly) [7227]
Number of TMSs:39
Substrate ions

Cross database links:

Entrez Gene ID: 34112   
Pfam: PF12166   
KEGG: dme:Dmel_CG8486   

References (2)

[1] “Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.”  Misra S.et.al.   12537572
[2] “The genome sequence of Drosophila melanogaster.”  Adams M.D.et.al.   10731132

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MVFSYACMVL QRIVVPAVLV LAALMRPVGI SFVYLLMFFV SPFVPLATRR NFKGSVTAFF 
61:	IILLTLSTLV LLGHITLQIL AVSLTLPIYN CSFSERLLRH IGFVSFIDLQ PFAIIEWLVP 
121:	EVLVFATSLG SYLTVKRVAS QPVGAEQLEN GEVVDGQAEN AQTSSQPSAA DANGGDVQQA 
181:	TVTTPLQQQQ QQLRKRVSMI SQHIHFEGLV KISPLFCLAT LFFAAVLRPS VPGGFYFLIF 
241:	LLSGTYWATC QTLQRGFALL LRCVMVVLVL HSLSIVSYQT PWMQSHLNHT TLTARLIGLE 
301:	PLIESYCSPD IRVFLYNNKL SLDSYLNPFA LFFAYFALAL TTKHLIKPRL EPKPATALGQ 
361:	QLDCNSSSIN NTTGNKVNRQ LSLLTSQTSR GRRDGSNPGG GGTTITTTTT TTSTTAIRNQ 
421:	RLSLVRQSTR KARTPQPLES GSSVAPSVTQ RGNDMQLESM EQRSEQENTT TSILDQISYG 
481:	FVSVGGFIYQ NSYIFTNILM MAWSIVYHSW LTFVLLLSAN VLWMIPNQRK AMMRSSPFIV 
541:	LYAEALLIAQ YIYGMDLNNE ELPTSVPTAG INLQQIGFER PIENQMRPCV PLIVKTAFVL 
601:	MFWVTSRQFF KEKRDRRRDS TLADFIAPLQ ITVGSAGSSY LINDGKKTSK FLKKAGDVIK 
661:	NLLVRLWIWL LVLVIFLCAI TGENMTGFRI CYMALFLFFL LVFQSSSKAW VKIMYGFWLF 
721:	LIFYAMSILI LIYTYQFDKF DTYWSDYLNV SATLQKDIGL KRYQTKDLFL HLVSPTIIVI 
781:	LTVIQVHYFH KRFIASLQQQ PLAGGSAQQK PTETTALEPA PSKRRGSAGS LRKSQGPSAE 
841:	AAPGATTDFE TSVRDLVRIS FRKIKNKSEY IFKNFKDVFW RFLELHIMKA VYIAAFVCSV 
901:	SEVCVLHIIF VGFCVLGATS RKAVQVVISR LISFIVTVIV LSKMIYQIEY LSHSQHNVVC 
961:	SDNRTANNAE WIGLTKADKV TGGLMSLLRT YIIYMVIVTM HAVISLRQLQ MRVKIGALNA 
1021:	PPTKLLFPNI IRADAEKDLV GLVKYLLNFG FYKFGIEISL IALVSTITYR QDIVAVVYAL 
1081:	WLVVLLLLRR SQCAKIWGVF QAFFAISILT QYIVLVGLPP SSCLVFPWDE GPFGEGIQRW 
1141:	AMLPGALHFN HVPKLIFDFI VLVILNRQKS IFCIEQRYAS NDDYPGGSNR SVIADIAQLG 
1201:	RVPFDNPTHD FCSYIRNYSD ILKNGVLCGF YWFTLAVVFL AGTNIADLLA LGYLIGAFIF 
1261:	LWQGSDFYLR PIHTIIFRWK WLLAFNVANI LIKTSFQMAG CLFMTQLTKD CCWLVHMLGI 
1321:	TCTSNVLTEQ IMLPEEAELA LKPGECPKIT HQVVLLWDTI CFAFIIFQLR IFKSHYFCHI 
1381:	ITDTKANNIL ASRGADIIES LRHKQIAHRH DHEKQVLHKI KRKMERIRAT QQKMLRPLDK 
1441:	QTHFDEHGYP LPAPTVRRRK EIKLHPHATR AGDYYMFEEM DDKFELDLIH DEIDFLEEEN 
1501:	ITESEMKMQR RKTLYDVWKD LNDAEYRRHF YMRERSYASE PGSRILLKLD DEKEKIGPDL 
1561:	GLASDHDEDD DTIECDLGMR TSTLSEPLDF GRRSQTLLEV KSKDAPTGEF PSTSKGISKE 
1621:	RDAATASSSA SPAPTRDVGD LPVIPPPSTG LGREQTSKET SDSKSKMEVD SGEVTAKDSD 
1681:	EDFDTNPIIR LLEGFLVTLT IRLNRFSRNY RFVNRILAGE KKTLKESSSL NRLGLSSAAA 
1741:	MFHFLKSNLE SDESEPPASS STPRRVVIAP PNATEHSDPT STTLNTNTTT TPLSPPEPLQ 
1801:	PLQPLQPNTT STPQQQHQHI RAAEEIIELP VDTVDGVAHR KQSINSSPPA KGTMLSRKSD 
1861:	CGLPEIRIKA PSIERGAHYY HNHHSGGGSG SLSKHWSYEQ VDSAGEFNLE EENFAQRDHH 
1921:	IIVEVLISSW YALLANTDLI CYIVVFINQV VNASLISLPL PIMVFLWGTL SLPRPTKTFW 
1981:	VTLIAYTQAI VLIKCIFQFK LIWSNYHQLP NQPLTPAKIF GVENKAHYAI YDLILLLVLF 
2041:	LHRYLLKSQG LWKSGYKDTD NQFTKPTASI DERDDSDNLS QPDSRQLNDD AAQKLSLQVS 
2101:	QASLPGSPEF SKTGINQLER TKYTSSLYKF FFSLVHKSRL ATDVYALMFL CDFVNFFVLL 
2161:	FGFTAFGTQQ TESDEGVQTY LAENKVPIPF LIMLLVQFLL IVIDRALYLR KALVNKIIFH 
2221:	FFSVIGIHIW MFFVVPAVTE RTFNSLAPPI IFYVIKCFYM LLSSYQIKSG YPKRILGNFF 
2281:	TKGFSMVNMI AFKVYMQIPF LYELRTILDW VCIDSTMTIF DWLKMEDIFS NIYLIRCTRQ 
2341:	SETDFPAMRA QKKASLSKLI MGGTIVLLIV ICIWGPLCLF ALGNAVGTSN VPFHVSLSIR 
2401:	IGPYDPIYTT NNYDSIFEIN PEMYSQMTNA YIKEKQALTF IAGYDATDVA AVRLAGNSPS 
2461:	LWNIAPPDRQ RLLNDLRNNH TLKARFSYSL TRKAPAKGLK ENVGDEHAIS LDESFEGRAA 
2521:	LIHMLSETHD VEPIYSNGTT NGTTPEVEEV VVIPGMIPKF IKVLNSGDAA VVSVLSPKHY 
2581:	DYRPLVIKMH RDNETNGLWW EIRDYCNDTF YNETLSKFAY SNCTSGIVMY TFNDKKFPST 
2641:	FSFLTAGGII GLYTTFVLLA SRFMKSFIGG QNRKIMFEDL PYVDRVLQLC LDIYLVREAL 
2701:	EFALEEDLFA KLLFLYRSPE TLIKWTRPKE EYVDDDGDTD SIPSRMSVRR PEQLQPQQPQ