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1.A.75.1.8
Mechanosensitive piezo channel protein, isoform a, of 2438 aas.  The C-terminal extracellular domain (before the last TMS) has a β-sandwich fold (Kamajaya et al. 2014).

Accession Number:Q17897
Protein Name:Protein C10C5.1, isoform a
Length:2438
Molecular Weight:276345.00
Species:Caenorhabditis elegans [6239]
Number of TMSs:39
Substrate cations

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTVPPLLKSC VVKLLLPAAL LAAAIIRPSF LSIGYVLLAL VSAVLPPIRK SLALPKLVGT 
61:	FVIITFLFCL AVALGVGSYQ ISEQVVHKND RTYICNRSDT TLFRSIGLVR FHPTGTFEST 
121:	RAFLPEIIAT SAALLTIIIV MFLSHRDEQL DVVGDVVTVR SESGREQRRQ RKLAAIMWSA 
181:	IGNSLRRLTN FVLFLFTAYV GIVKPSLSNS IYFLAFLFIS TWWSTYTPLR HGVYNQIKKF 
241:	LIFYSALHFL VLYTYQIPIV HHSWLPTGSF LPRLFGLTVL MDSSCPEWWK FPFVAPDFND 
301:	DDLIMKWPLY ANPIVVLVFF YLTVAQYKFT RNGSREYIDD NEYGSSVHEE RFVSAGTVET 
361:	NVDDVGQLIS ISESTASAPS GRGRGNTLLL SNASSSANDD EQGRARSRSP LRNGEEQGSI 
421:	PLRKVTSQVV DRNKLSNIFN TPGDKESAAS KGMIAVMTFV IFHSYSIALT AMMTWALLYH 
481:	SIFGLILLIL TCILWIFRDT RKSSFAMAPI ILMYIEFLLI LQYFLSMDIH AEIGDPAWMN 
541:	FVGIEWTTLP VHAVIILCVQ TLLTLPVFLL LRLARREKFY ESLSDYERQR RINSYGTFGA 
601:	SKTGAGGVAV AKDPKSRKFA AFVEYLSNKV SVYFIFVVSV VLLVVSTCFA PNFYNILFFA 
661:	LWALNLIYLK FSFRLYRGLA YAFWLTLTFY TSIVIIALYI YQFPGVSQWI IRNTSLSQEW 
721:	LNAIGLVDFR AIGESGALFL QLLAPIALFV VTMLQLKFFH GPWSRATSPR RAENDPPTST 
781:	TEAAAVASTS GTQGRAHAAG DTLVKKLHKL ANQTIELLWR FFEVHISKIV FVIIAIFIAN 
841:	NINALYIPLV ILLSLAICLP SAADGIFSLF MCAYLFLVAL SKMIYQLDIV PELSQIDRGV 
901:	GADNCSHGNI SMPEWFGLKK EVEGTEPIYM LFGVIVSIIA LAFQSIVIYR QRHYRASLGL 
961:	PESMRAKVFP DFHHSHFDRS LKNAIQFLID YGFYKFGLEI TMIAIGIDIF NRMDALAAIQ 
1021:	CFWLVLFALN KRVFVRRIWV FYVIYMAILY PLQFFSYVGL PPDSCIEYPW SYWIPSYSDD 
1081:	ARFNLSYLLN LSIYGVNWPS AYLIGDFFVL LLASCQLAVF RREGEDNDSI YNDGNFVIKP 
1141:	ENPQYDFIDT KKSYVDYFKS FVFHYGHWIT LMSTLAAGIA GTSLFALGYI IFTLTMLWSG 
1201:	NNLYVMNSTL RSFEHTLKRW NALLGYTLFT ITMKVCLQIF GCVFLSWFDQ SGGWGKTLCI 
1261:	VRQLFSITCV NNECHVLKEL EDFSKACAVE TKEGNIGFDV IALSFLVFQI RIFHSWYFQH 
1321:	CMVEYRSEVI LANRGAVLKN QLIEKEMKEQ NEQQKAKFND IRRRTEAIRE RYQKQIERGA 
1381:	AERDFEPVTY GHAKRAGDYY MFKYDPENDD LVEPVDSFVP EVDPKATAYD RLDPGQIMYA 
1441:	ATAHDLDLAK TVQQVKKGDT IKDPDSRALI AVSEPEARKP GGTEETDGDE DEDNKDSKVE 
1501:	STAKFIQKMI ASALDLCSVT LNKLCREHRY VGFVLSKEKQ KLKSGHSESL SNTSRKLTDI 
1561:	RSAVDLPSLQ LVQSANDVEK METAVSVDWQ QKSSATRLLN AVVNCIGAHT DILCYFFAIM 
1621:	TQVMTGGLIT LPLPLMSLFW GNLSNPRPSK FFWVTMITYT ECVIVIKFVC QFAFMPYNSI 
1681:	TWRTEHQMDP MSLDKLFGVS QRDSFALWDI VLLFSLFFHR YMLRKLGLWK DANLTDTFTL 
1741:	KEEPRSASGS DTGSPKKIAQ EPKVVVTQSD TLEGTSGGEI VIPSDPNAVS NMEELDCEPP 
1801:	IPEKQSGPIG RFIHQLFHPK FRYIRDLYPI MFGIDVICFL IMTFGYSAFG EGGSGNVLDD 
1861:	VKASRIPVTL VVMLVGMTLA IIIDRALYLR KSVVGKLIYQ VLMIAFLHIW VFLVLPNMTR 
1921:	RSAISNHVAQ ALYVIKSCYF LVSAWQIRNG YPELCIGNLL THSYGMTNMI AFKVFMNIPF 
1981:	LFELRTAIDW TWTDTSMPLF DFFNMENFYA HIFNIKCARQ FEAAYPAPRG IPKGKLVKYM 
2041:	MGFPIIIGVV IFIFSPLLLW SLLNQIGTIS MPEKVTLRIS IEGYPPLYEM EAQGSNHDNA 
2101:	ELGMIKPDQL ASLNQALTDS YTTRDTNSIL RSRMSVSYLK GYTYEDILIV RFRPESEIYW 
2161:	PISQDSRNAM IDKLSRNTSV NFEVSLEFTR PYDPNENAAL KHSKSWLVPI SLDMTIRAKI 
2221:	QSALRGDPGH PILIPQSIPA FIQVPNQGEL TLPTSIGNTI INDGNPRINT TGMEKSDEAR 
2281:	AWFDSLTLNL EQGKSQNEKM WIATSEHPGD QNAKLWIKTA NTTYSGRPYL QVVGFIDRAF 
2341:	PSFLAKVFKG GVIAVYLSVI LVVGRGLVRG IFTTSPSTVM FTELPNADHL LKICLDIYLV 
2401:	REAKDFMLEQ DLFAKLIFLF RSPATLIEWT RMSKKKQE