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1.A.77.1.7
Channel homologue. Putative 5TMS protein (307 aas) with homology to MCU Ca2+/Mg2+ channels in the C-terminal 2TMS domain. The N-terminal domain is found only in Trypanosoma and Leishmania species.

Accession Number:D0A5S5
Protein Name:Putative uncharacterized protein
Length:307
Molecular Weight:34858.00
Species:Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) [679716]
Number of TMSs:3
Substrate Mg2+, Ca2+

Cross database links:

Pfam: PF04678   

References (1)

[1] “The genome sequence of Trypanosoma brucei gambiense, causative agent of chronic human african trypanosomiasis.”  Jackson A.P.et.al.   20404998

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MWRPYTLFVV PMRFGSPLQL RSLLVSRMPG RFDAFLTRRF VSTATPGGQP TCSDSHNSAA 
61:	CLTAEEFSNI VPMFLLGQAL RQHTSNEENR AGAGEFVITR EVFNRYCSES RVEDTDKALQ 
121:	LLCESGVVVS ISDGAAVHLR PVQFLQMHND AADASDAKVK TPFEDYIRAA QNRLADAEAE 
181:	EMAMRVALQP AIDNAAKRRR LLWSGALCLM AVQLAVISRL TFVDLDWDIM EPVSYFLGSG 
241:	TSILFLIYLL RNGRVKSYKE YEEKAAASRV RLHAPADFEW RKYDAVVRRV EVEKNMVEQM 
301:	RKWFKHH