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1.A.8.10.1
Tonoplast intrinsic protein

Accession Number:P26587
Protein Name:TIPA aka TIP3.1 aka AT1G73190 aka T18K17.14
Length:268
Molecular Weight:28308.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Vacuole membrane1 / Multi-pass membrane protein2
Substrate water

Cross database links:

Genevestigator: P26587
eggNOG: KOG0223
HEGENOM: HBG705794
RefSeq: NP_177462.1   
Entrez Gene ID: 843653   
Pfam: PF00230   
KEGG: ath:AT1G73190   

Gene Ontology

GO:0042807 C:central vacuole
GO:0016021 C:integral to membrane
GO:0009705 C:plant-type vacuole membrane
GO:0000326 C:protein storage vacuole
GO:0005215 F:transporter activity
GO:0006914 P:autophagy
GO:0055085 P:transmembrane transport

References (5)

[1] “Vegetative and seed-specific forms of tonoplast intrinsic protein in the vacuolar membrane of Arabidopsis thaliana.”  Hoefte H.R.et.al.   16668923
[2] “Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.”  Theologis A.et.al.   11130712
[3] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172
[4] “Characterization of a new vacuolar membrane aquaporin sensitive to mercury at a unique site.”  Daniels M.J.et.al.   8624437
[5] “From genome to function: the Arabidopsis aquaporins.”  Quigley F.et.al.   11806824

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MATSARRAYG FGRADEATHP DSIRATLAEF LSTFVFVFAA EGSILSLDKL YWEHAAHAGT 
61:	NTPGGLILVA LAHAFALFAA VSAAINVSGG HVNPAVTFGA LVGGRVTAIR AIYYWIAQLL 
121:	GAILACLLLR LTTNGMRPVG FRLASGVGAV NGLVLEIILT FGLVYVVYST LIDPKRGSLG 
181:	IIAPLAIGLI VGANILVGGP FSGASMNPAR AFGPALVGWR WHDHWIYWVG PFIGSALAAL 
241:	IYEYMVIPTE PPTHHAHGVH QPLAPEDY