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1.A.9.1.19
Acetyl choline binding protein, AchBP, of 229 aas, corresponding to the N-terminal extracellular domain of AcChRs.  The crystal structure is known (Lin et al. 2016).  It modulates synaptic transmission (Smit et al. 2001). This soluble protein has enhanced our understanding of the requirements for agonistic and antagonistic interactions at the ligand recognition site of the nAChRs. Camacho-Hernandez and Taylor 2020 have reviewed the potential and limitations of soluble surrogates, termed the AChBP family, in drug development.

Accession Number:P58154
Protein Name:Acetylcholine-binding protein
Length:229
Molecular Weight:26061.00
Species:Lymnaea stagnalis (Great pond snail) [6523]
Location1 / Topology2 / Orientation3: Cell junction1
Substrate

Cross database links:

Structure:
1I9B   1UV6   1UW6   1UX2   1YI5   2ZJU   2ZJV   3U8J   3U8K   3U8L   [...more]

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FASTA formatted sequence
1:	MRRNIFCLAC LWIVQACLSL DRADILYNIR QTSRPDVIPT QRDRPVAVSV SLKFINILEV 
61:	NEITNEVDVV FWQQTTWSDR TLAWNSSHSP DQVSVPISSL WVPDLAAYNA ISKPEVLTPQ 
121:	LARVVSDGEV LYMPSIRQRF SCDVSGVDTE SGATCRIKIG SWTHHSREIS VDPTTENSDD 
181:	SEYFSQYSRF EILDVTQKKN SVTYSCCPEA YEDVEVSLNF RKKGRSEIL