TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


1.B.1.5.2
PorA porin, cation selective at pH > 6; anion selective at pH < 4 (a continuum electrodiffusion model accounts for the results) (Cervera et al., 2008)

Accession Number:Q05520
Protein Name:PorA
Length:348
Molecular Weight:37684.00
Species:Neisseria meningitidis [487]
Location1 / Topology2 / Orientation3: Cell outer membrane1 / Multi-pass membrane protein2
Substrate ions

Cross database links:

Pfam: PF00267   

Gene Ontology

GO:0009279 C:cell outer membrane
GO:0005886 C:plasma membrane
GO:0046930 C:pore complex
GO:0005215 F:transporter activity
GO:0006811 P:ion transport

References (3)

[1] “Comparison of the class 1 outer membrane proteins of eight serological reference strains of Neisseria meningitidis.”  Maiden M.C.et.al.   1904526
[2] “Topology of outer membrane porins in pathogenic Neisseria spp.”  van der Ley P.et.al.   1652557
[3] “The porA gene in serogroup A meningococci: evolutionary stability and mechanism of genetic variation.”  Suker J.et.al.   8057850

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	EGRNIQLQLT EPLQNIQQPQ VTKRKSRIRT KISDFGSFIG FKGSEDLGEG LKAVWQLEQD 
61:	VSVAGGGATR WGNRESFVGL AGEFGTLRAG RVANQFDDAS KAIDPWDSNN VVASQLGIFK 
121:	RHDDMPVSVR YDSPEFSGFS GSVQFVPAQN SKSAYTPAHF VQQTPESQPT LVPAVVGKPG 
181:	SDVYYAGLNY KNGGFAGNYA FKYAKHANVG RDAFELFLLG SGSDEAKGTD PLKNHQVHRL 
241:	TGGYEEGGLN LALAAQLDLS ENADKTKNST TEIAATASYR FGNAVPRISY AHGFDFIERG 
301:	KKGENTSYDQ IIAGVDYDFS KRTSAIVSGA WLKRNTGIGN YTQINAAS