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1.B.23.1.24
Major envelope protein, Mep45, of 432 aas and 1 N-terminal TMS.  Mep45 contains two distinct domains: an N-terminal S-layer homologous (SLH) domain that protrudes into the periplasm and binds to peptidoglycan, and the remaining C-terminal transmembrane domain that forms a non-selective pore able to transport molecules of <600 Da (Kojima et al. 2016). The estimated pore radius is 0.58 nm; truncation of the SLH domain does not affect the channel.

Accession Number:Q25BZ4
Protein Name:Major envelope protein
Length:432
Molecular Weight:47805.00
Species:Selenomonas ruminantium [971]
Number of TMSs:1
Substrate small molecules

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  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKKTLVSALT TALVVGAAST TFAASNPFSD VPADHWAYDA VAQLAADGVV EGYGDSTFKG 
61:	NRNITRYEMA QMVAKAMAKN TSGTDKALVD KLAAEFAEEL NNLGVRVSNL ERNADMVKWN 
121:	GVAEYTFTRQ RHEKNGKKTT NHGDDNVLFR LEPSAEVNSH WHVKARLDAN SNLKSDQGED 
181:	SSSVKLKRVW AQGEYGKLTV KLGKFASLND DTFADTPFSG AEVSYGKDVK VIAAAGRLNL 
241:	WDASAFKKNV DIQNVRNWMV AGRHDDRTAN YQYAGLELNK SKLSGGLYWH HLNAAGFDYK 
301:	KGTTDEANIG AVKGSYTFSK NVSVNGFYTQ NFDVDTKNYQ DKSASLEVDY KGAQQENKGT 
361:	WGAWVAYRRL GNAAIINNTY DVINTGYKGW EVGGNYTLFK NVVTTLRYGN QKDISNSNVK 
421:	DQNFFGRVQF FF