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1.B.25.1.5
GusC (UidC) putative glucuronide porin (Liang et al., 2005).  Reported to enhance the activity of the UidB (GusB) glucuronide transporter (TC# 2.A.2.1.5). Glucuronide transport does not occur in strain K12 due to a variant at position 100 of the UidB protein.

Accession Number:Q47706
Protein Name:GusC aka UidC
Length:421
Molecular Weight:46648.00
Species:Escherichia coli [83333]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Cell outer membrane1
Substrate Glucuronides

Cross database links:

Genevestigator: Q47706
EchoBASE: EB2534
EcoGene: EG12668
HEGENOM: HBG467031
DIP: DIP-11088N
RefSeq: AP_002236.1    NP_416132.2   
Entrez Gene ID: 944820   
Pfam: PF03573   
BioCyc: EcoCyc:G6866-MONOMER    ECOL168927:B1615-MONOMER   
KEGG: ecj:JW1607    eco:b1615   

Gene Ontology

GO:0009279 C:cell outer membrane
GO:0005886 C:plasma membrane
GO:0046930 C:pore complex
GO:0015288 F:porin activity
GO:0008643 P:carbohydrate transport
GO:0006811 P:ion transport

References (3)

[1] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[2] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[3] “The gusBC genes of Escherichia coli encode a glucuronide transport system.”  Liang W.-J.et.al.   15774881

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MRKIVAMAVI CLTAASGLTS AYAAQLADDE AGLRIRLKNE LRRADKPSAG AGRDIYAWVQ 
61:	GGLLDFNSGY YSNIIGVEGG AYYVYKLGAR ADMSTRWYLD GDKSFGFALG AVKIKPSENS 
121:	LLKLGRFGTD YSYGSLPYRI PLMAGSSQRT LPTVSEGALG YWALTPNIDL WGMWRSRVFL 
181:	WTDSTTGIRD EGVYNSQTGK YDKHRARSFL AASWHDDTSR YSLGASVQKD VSNQIQSILE 
241:	KSIPLDPNYT LKGELLGFYA QLEGLSRNTS QPNETALVSG QLTWNAPWGS VFGSGGYLRH 
301:	AMNGAVVDTD IGYPFSLSLD RNREGMQSWQ LGVNYRLTPQ FTLTFAPIVT RGYESSKRDV 
361:	RIEGTGILGG MNYRVSEGPL QGMNFFLAAD KGREKRDGST LGDRLNYWDV KMSIQYDFML 
421:	K