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1.B.3.1.2
Oligosaccharide porin, ScrY (transports sucrose, raffinose and maltooligo-saccharides) (Kim et al. 2002).  The 3-d structure known (PDB ID 1A0S).  Sucrose translocation through the pore showed two main energy barriers within the constriction region of ScrY. Three asparate residues are key residues, opposing the passage of sucrose, all located within the L3 loop (Sun et al. 2016).

Accession Number:P22340
Protein Name:ScrY
Length:505
Molecular Weight:55467.00
Species:Salmonella typhimurium [90371]
Location1 / Topology2 / Orientation3: Cell outer membrane1 / Multi-pass membrane protein2
Substrate Sucrose, Raffinose, Maltooligosaccharides

Cross database links:

Pfam: PF02264   
Drugbank: Drugbank Link   

Gene Ontology

GO:0009279 C:cell outer membrane
GO:0005886 C:plasma membrane
GO:0046930 C:pore complex
GO:0005351 F:sugar:hydrogen symporter activity
GO:0008643 P:carbohydrate transport
GO:0006811 P:ion transport

References (3)

[1] “Plasmid-mediated sucrose metabolism in Escherichia coli: characterization of scrY, the structural gene for a phosphoenolpyruvate-dependent sucrose phosphotransferase system outer membrane porin.”  Hardesty C.et.al.   1846143
[2] “A sugar-specific porin, ScrY, is involved in sucrose uptake in enteric bacteria.”  Schmid K.et.al.   1649946
[3] “Structure of the sucrose-specific porin ScrY from Salmonella typhimurium and its complex with sucrose.”  Forst D.et.al.   9437428
Structure:
1A0S   1A0T   1OH2     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MYRKSTLAML IALLTSAASA HAQTDISTIE ARLNALEKRL QEAENRAQTA ENRAGAAEKK 
61:	VQQLTAQQQK NQNSTQEVAQ RTARLEKKAD DKSGFEFHGY ARSGVIMNDS GASTKSGAYI 
121:	TPAGETGGAI GRLGNQADTY VEMNLEHKQT LDNGATTRFK VMVADGQTSY NDWTASTSDL 
181:	NVRQAFVELG NLPTFAGPFK GSTLWAGKRF DRDNFDIHWI DSDVVFLAGT GGGIYDVKWN 
241:	DGLRSNFSLY GRNFGDIDDS SNSVQNYILT MNHFAGPLQM MVSGLRAKDN DERKDSNGNL 
301:	AKGDAANTGV HALLGLHNDS FYGLRDGSSK TALLYGHGLG AEVKGIGSDG ALRPGADTWR 
361:	IASYGTTPLS ENWSVAPAML AQRSKDRYAD GDSYQWATFN LRLIQAINQN FALAYEGSYQ 
421:	YMDLKPEGYN DRQAVNGSFY KLTFAPTFKV GSIGDFFSRP EIRFYTSWMD WSKKLNNYAS 
481:	DDALGSDGFN SGGEWSFGVQ METWF