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1.B.32.1.1
Non-specific FomA porin precursor (Kleivdal et al. 1995). The N-terminal region is periplasmic while the C-terminus is a 14 stranded β-barrel (Puntervoll et al. 2002).  The β-barrel may have a tilt angle of 45° relative to the barrel axis (Anbazhagan et al., 2008). FomA is fusogenic (Pszon-Bartosz et al., 2011).  The N-terminal region is periplasmic while the C-terminus is a 14-stranded β-barrel (Puntervoll et al. 2002). Its unique solute transport activity with size exclusion limit has been described (Kattner et al. 2015).

Accession Number:Q47905
Protein Name:FomA
Length:370
Molecular Weight:42241.00
Species:Fusobacterium nucleatum subsp [76857]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell outer membrane1 / Multi-pass membrane protein2
Substrate small molecules

Cross database links:

References (1)

[1] “Sequence variability of the 40-kDa outer membrane proteins of Fusobacterium nucleatum strains and a model for the topology of the proteins.”  Bolstad A.I.et.al.   8041356

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKKLALVLGL LLVVGSVASA KEVMPAPTPA PEKVVEYVEK PVIVYRDREV APAWRPNGSV 
61:	DVQYRWYGEV EKKNPKDDKD ENWATGKVNA GRLQTLTKVN FTEKQTLEVR TRNHHTLNDT 
121:	DANNKKSNGA ADEYRLRHFY NFGKLGSSKV NATSRVEFKQ KTNDGEKSLG ASVLFDFADY 
181:	IYSNNFFKVD KLGLRPGYKY VWKGHGNGEE GTPTVHNEYH LAFESDFTLP FNFALNLEYD 
241:	LSYNRYREKF ETTDGLKKAE WYGELTAVLS NYTPLYKAGA FELGFNAEGG YDTYNMHQYK 
301:	RIGGEDGTSV DRRDYELYLE PTLQVSYKPT DFVKLYAAAG ADYRNRITGE SEVKRWRWQP 
361:	TASAGMKVTF