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1.B.33.1.2
Protective surface antigen D15 precursor.  The high resolution 3-d structure of the H. ducreyi orthologue has been solved (Noinaj et al. 2013).

Accession Number:P46024
Protein Name:D15
Length:797
Molecular Weight:87676.00
Species:Haemophilus influenzae [727]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell outer membrane1
Substrate proteins

Cross database links:

Pfam: PF01103    PF07244   

Gene Ontology

GO:0009279 C:cell outer membrane
GO:0005886 C:plasma membrane

References (2)

[1] “The sequencing of the 80-kDa D15 protective surface antigen of Haemophilus influenzae.”  Flack F.S.et.al.   7737523
[2] “Outer membrane protein D15 is conserved among Haemophilus influenzae species and may represent a universal protective antigen against invasive disease.”  Loosmore S.M.et.al.   9284140

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MKKLLIASLL FGTTTTVFAA PFVAKDIRVD GVQGDLEQQI RASLPVRAGQ RVTDNDVANI 
61:	VRSLFVSGRF DDVKAHQEGD VLVVSVVAKS IISDVKIKGN SVIPTEALKQ NLDANGFKVG 
121:	DVLIREKLNE FAKSVKEHYA SVGRYNATVE PIVNTLPNNR AEILIQINED DKAKLASLTF 
181:	KGNESVSSST LQEQMELQPD SWWKLWGNKF EGAQFEKDLQ SIRDYYLNNG YAKAQITKTD 
241:	VQLNDEKTKV NVTIDVNEGL QYDLRSARII GNLGGMSAEL EPLLSALHLN DTFRRSDIAD 
301:	VENAIKAKLG ERGYGSATVN SVPDFDDANK TLAITLVVDA GRRLTVRQLR FEGNTVSADS 
361:	TLRQEMRQQE GTWYNSQLVE LGKIRLDRTG FFETVENRID PINGSNDEVD VVYKVKERNT 
421:	GSINFGIGYG TESGISYQAS VKQDNFLGTG AAVSIAGTKN DYGTSVNLGY TEPYFTKDGV 
481:	SLGGNVFFEN YDNSKSDTSS NYKRTTYGSN VTLGFPVNEN NSYYVGLGHT YNKISNFALE 
541:	YNRNLYIQSM KFKGNGIKTN DFDFSFGWNY NSLNRGYFPT KGVKASLGGR VTIPGSDNKY 
601:	YKLSADVQGF YPLDRDHLWV VSAKASAGYA NGFGNKRLPF YQTYTAGGIG SLRGFAYGSI 
661:	GPNAIYAEYG NGSGTGTFKK ISSDVIGGNA IATASAELIV PTPFVSDKSQ NTVRTSLFVD 
721:	AASVWNTKWK SDKNGLESDV LKRLPDYGKS SRIRASTGVG FQWQSPIGPL VFSYAKPIKK 
781:	YENDDVEQFQ FSIGGSF