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1.B.35.1.1
The oligogalacturonate-specific porin, KdgM.  The 3-D structure is known at 1.9 Å resolution (Hutter et al. 2014).  KdgM folds into a 12-stranded antiparallel beta-barrel with a circular cross-section defining a transmembrane pore with a minimal radius of 3.1 Å. Most loops that face the cell exterior in vivo are disordered but nevertheless mediate contact between densely packed membrane-like layers in the crystal. The channel is lined by two tracks of arginine residues facing each other across the pore, a feature that is conserved within the KdgM family and is likely to facilitate the diffusion of acidic oligosaccharides (Hutter et al. 2014).

Accession Number:Q934G3
Protein Name:KdgM
Length:236
Molecular Weight:26723.00
Species:Erwinia chrysanthemi [198628]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell outer membrane1
Substrate Oligogalacturonate

Cross database links:

Pfam: PF06178   

Gene Ontology

GO:0009279 C:cell outer membrane
GO:0005886 C:plasma membrane
GO:0046930 C:pore complex
GO:0008643 P:carbohydrate transport
GO:0006811 P:ion transport
GO:0009405 P:pathogenesis

References (1)

[1] “The oligogalacturonate-specific porin KdgM of Erwinia chrysanthemi belongs to a new porin family.”  Blot N.et.al.   11773048
Structure:
4FQE   4PR7     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MKIKLLTLAV ASLVSVNALA VSIDYRHEMQ DTAQAGHKDR LLISHRFANG FGLSSEVKWA 
61:	QSSADKTPNK PFNEQVSNGT EVVASYVYKF NSVFSIEPGF SLESGSSNNN YRPYLRGRAN 
121:	VTDDLSVALR YRPYFKRNSG NIGKDNTMDK GYTLTGNIDY TFLKDYTIGY ELEYKKGTSG 
181:	KTILSDNDDY DITHNVKLSY KWDKNWKPYV EVGNVSGSET TDERQTRYRV GVQYSF