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View Proteins belonging to: The Brucella-Rhizobium Porin (BRP) Family

1.B.4 The Brucella-Rhizobium Porin (BRP) Family

The porin proteins in the BRP family are found in the Agrobacterium, Bartonella, Brucella, Mesorhizobium and Rhizobium genuses and are likely to be found in other closely related genera. Brucella species have two homologous outer membrane porins, Omp2a and Omp2b, encoded by two closely linked genes oriented in oppostie directions. Omp2 proteins exist in many size variants due to multiple gene conversions between the two homologous genes that lead to chimeric proteins. These variants show different permeability to sugars as well as different ion conductivities (Paquet et al, 2001). This family is also called the Omp2 family in SwissProt.

View Proteins belonging to: The Brucella-Rhizobium Porin (BRP) Family

References associated with 1.B.4 family:

Cheng, N.H., J.K. Pittman, T. Shigaki, and K.D. Hirschi. (2002). Characterization of CAX4, an Arabidopsis H+/cation antiporter. Plant Physiol. 128: 1245-1254. 11950973
Cloeckaert, A., H.S. Debbarh, N. Vizcaino, E. Saman, G. Dubray, and M.S. Zygmunt. (1996). Cloning, nucleotide sequence, and expression of the Brucella melitensis bp26 gene coding for a protein immunogenic in infected sheep. FEMS Microbiol. Lett. 140: 139-144. 8764475
Cloeckaert, A., J.M. Verger, M. Grayon, and N. Vizcaino. (1996). Molecular and immunological characterization of the major outer membrane proteins of Brucella. FEMS Microbiol Lett. 145: 1-8. 8931319
Hohle, T.H. and M.R. O'Brian. (2009). The mntH gene encodes the major Mn2+ transporter in Bradyrhizobium japonicum and is regulated by manganese via the Fur protein. Mol. Microbiol. 72: 399-409. 19298371
Hohle, T.H., W.L. Franck, G. Stacey, and M.R. O'Brian. (2011). Bacterial outer membrane channel for divalent metal ion acquisition. Proc. Natl. Acad. Sci. USA 108: 15390-15395. 21880957
Jeanteur, D., J.H. Lakey, and F. Pattus. (1991). The bacterial porin superfamily: sequence alignment and structure prediction. Mol. Microbiol. 5: 2153-2164. 1662760
Jeanteur, D., J.H. Lakey, and F. Pattus. (1994). The porin superfamily: diversity and common features. In: Bacterial Cell Wall. Edited by Ghuysen, J.M., Hakenbeck, R. Elsevier, Amsterdam, pp. 363-380.
Mei, H., N.H. Cheng, J. Zhao, S. Park, R.A. Escareno, J.K. Pittman, and K.D. Hirschi. (2009). Root development under metal stress in Arabidopsis thaliana requires the H+/cation antiporter CAX4. New Phytol 183: 95-105. 19368667
Nikaido, H. (1992). Porins and specific channels of bacterial outer membranes. Mol. Microbiol. 6: 435-442. 1373213
Paquet, J-.Y., M.A. Diaz, S. Genevrois, M. Grayon, J-.M. Verger, X. DeBolle, J.H. Lakey, J-.J. Letesson, and A. Cloeckaert. (2001). Molecular, antigenic, and functional analyses of Omp2b porin size variants of Brucella spp. J. Bacteriol. 183: 4839-4847. 11466287
Schulz, G.E. (1996). Porins: general to specific, native to engineered passive pores. Curr. Opin. Struc. Biol. 6: 485-490. 8794162
Vizcaino, N., A. Cloeckaert, M.S. Zygmunt, and G. Dubray. (1996). Cloning, nucleotide sequence, and expression of the Brucella melitensis omp31 gene coding for an immunogenic major outer membrane protein. Infect Immun. 64: 3744-3751. 8751924