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1.B.40.1.1
YadA consists of 3 domains: an adhesion head, a stalk involved in serum resistance, and an anchor that forms a pore for auto-transport (Grosskinsky et al., 2007).

Accession Number:P0C2W0
Protein Name:Adhesin yadA
Length:422
Molecular Weight:44155.00
Species:Yersinia enterocolitica [630]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell outer membrane1
Substrate proteins

Cross database links:

RefSeq: NP_783714.1   
Entrez Gene ID: 1239224   
Pfam: PF05658    PF05662    PF03895   

Gene Ontology

GO:0009279 C:cell outer membrane
GO:0005886 C:plasma membrane
GO:0005518 F:collagen binding
GO:0007155 P:cell adhesion
GO:0009405 P:pathogenesis

References (4)

[1] “DNA sequence and analysis of the pYVa127/90 virulence plasmid of Yersinia enterocolitica strain A127/90.”  Foultier B.et.al.   14527656
[2] “Binding to collagen by Yersinia enterocolitica and Yersinia pseudotuberculosis: evidence for yopA-mediated and chromosomally encoded mechanisms.”  Emoedy L.et.al.   2592347
[3] “Molecular analysis of transport and oligomerization of the Yersinia enterocolitica adhesin YadA.”  Roggenkamp A.et.al.   12813066
[4] “Structure and sequence analysis of Yersinia YadA and Moraxella UspAs reveal a novel class of adhesins.”  Hoiczyk E.et.al.   11080146
Structure:
3H7X   3H7Z   2lme     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
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FASTA formatted sequence
1:	MTKDFKISVS AALISALFSS PYAFANNDEV HFTAVQISPN SDPDSHVMIF QPEVRAPGGT 
61:	NALAKGTHSI AVGASAEAAE RAAVAVGAGS IATGVNSVAI GPLSKALGDS AVTYGAGSTA 
121:	QKDGVAIGAR ASTSDTGVAV GFNSKVDAKN SVSIGHSSHV AVDHDYSIAI GDRSKTDRKN 
181:	SVSIGHESLN RQLTHLAAGT KDTDAVNVAQ LKKEIEKTQE NANKKSAEVL GIANNYTDSK 
241:	SAETLENARK EAFDLSNDAL DMAKKHSNSV ARTTLETAEE HTNKKSAETL ASANVYADSK 
301:	SSHTLKTANS YTDVTVSNST KKAIRESNQY TDHKFHQLDN RLDKLDTRVD KGLASSAALN 
361:	SLFQPYGVGK VNFTAGVGGY RSSQALAIGS GYRVNESVAL KAGVAYAGSS DVMYNASFNI 
421:	EW