TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


1.B.6.1.4
HMP-AB outer membrane porin, OmpAb or Omp38 (Gribun et al., 2004).  It is the principle porin with an inner diameter of 2 nm which allows transport of cephalothin, cephaloridine, other antibiotics as well as other small molecules across the outer membrane (Sugawara and Nikaido 2012). Structural studies have been reported (Vashist and Rajeswari 2006). It is a secreted emulifier in some strains of Acinetobacter (Walzer et al. 2006). The sequence provided may be slightly incorrect (see the Q6BYW5 sequence of 356 aas).

Accession Number:Q8KWW6
Protein Name:HMP-AB outer membrane porin
Length:346
Molecular Weight:37817.00
Species:Acinetobacter baumannii [470]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Cepahlothin, Cepthaloridine, antibiotics, small molecules

Cross database links:

Pfam: PF00691    PF05736   

Gene Ontology

GO:0009279 C:cell outer membrane
GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
Window Size: Angle:  
FASTA formatted sequence
1:	MKLSRIALAT MLVAAPLAAA NAGVTVTPLL LGYTFQDTQH NNGGKDGELT NGPELQDDLF 
61:	VGAALGIELT PWLGFEAEYN QVKGDVDGLA AGAEYKQKQI NGNFYVTSDL ITKNYDSKIK 
121:	PYVLLGAGHY KYEIPDLSYH NDEEGTLGNA GVGAFWRLND ALSLRTEARG NLYFDEKFWN 
181:	YTALAGLNVV LGGHLKPAAP VVEVAPVEPT PVAPQPQELT EDLNMELRVF FDTNKSNIKD 
241:	QYKPEIAKVA EKLSEYPNAT ARIEGHTDNT GPRKLNERLS LARANSVKSA LVNEYNVDAS 
301:	RLSTQGFAWD QPIADNKTKE GRAMNRRVFA TITGSRTVLA EQPVAQ