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1.B.73.1.1
The outer membrane group 1 antigen capsule biogenesis/assembly protein, Wzi of 477 aas.  It forms an 18 stranded beta barrel, is a lectin, and plays a role in generating the end product of capsule assembly (Rahn et al. 2003). The 2.6 Å structure reveals long extracellular loops that block the barrel entrance while a helical bundle blocks the other end of the pore (Bushell et al. 2013). Also functions as a passive bidirectional water specific porin (Sachdeva et al. 2016Sachdeva et al. 2016).

Accession Number:Q5MQC2
Protein Name:Outer membrane protein
Length:477
Molecular Weight:52770.00
Species:Escherichia coli [562]
Number of TMSs:1
Substrate Capsular polysaccharides

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MIKIARIAVT LGLLSSLGAQ AYAAGLVVND NDLRNDLAWL SDRGVIHLSL STWPLSQEEI 
61:	ARALKKAKPS YSSEQVVLAR INQRLSALKA DFRVTGYTST DQPGTPQGFG QTQPADNSLG 
121:	LAFNNSGEWW DVHLQGNVEG GERISNGSRF NANGAYGAVK LWNQWLSFGQ VPQWWGPGYE 
181:	GSLIRGDAMR PMTGFLMQRA EQAAPETWWL RWVGPWQYQI SASQMNQYTV YPHTKIIGGR 
241:	FTFTPFQSLE LGASRIMQWG GQGRPQSFSS FWDGFTGHDN TGTDNEPGNQ LAGFDFKFKL 
301:	EPTLGWPVSF YGQIIGEDEA GYLPSSNMFL AGVEGHHSLG KNAVNWYVEA HDTRTNMSGT 
361:	RYSYWHHIYT DGYYQQGYPL GDAMGGDGQL LAGKIELMTE SNQRWSTRLV FAKVNPDNLV 
421:	INGAFPHSDT LKGVQLGWGG DVYQSVRLNT SLWYTNANNS DSDDVGASAG IEIPFSL