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1.B.8.1.12
Mitochondrial outer membrane voltage-dependent anion-selective channel protein 2, VDAC-2 of 294 aas.  Protein:micelle rations and cysteine residues in the protein influence VDAC2 stability and unfolding rates (Maurya and Mahalakshmi 2014; Maurya and Mahalakshmi 2014).  VDAC-2  performs a different subset of regulatory functions than VDAC1. It has anti-apoptotic features and contributes to gametogenesis.It may also regulate ROS, steroidogenesis and mitochondria-associated endoplasmic reticulum membrane regulatory pathways (Maurya and Mahalakshmi 2015).  Plays a role in mitochondrial import of Bak and tBid-induced apoptosis (Naghdi et al. 2015).

Accession Number:P45880
Protein Name:Voltage-dependent anion-selective channel protein 2
Length:294
Molecular Weight:31567.00
Species:Homo sapiens (Human) [9606]
Location1 / Topology2 / Orientation3: Mitochondrion outer membrane1
Substrate anions

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FASTA formatted sequence
1:	MATHGQTCAR PMCIPPSYAD LGKAARDIFN KGFGFGLVKL DVKTKSCSGV EFSTSGSSNT 
61:	DTGKVTGTLE TKYKWCEYGL TFTEKWNTDN TLGTEIAIED QICQGLKLTF DTTFSPNTGK 
121:	KSGKIKSSYK RECINLGCDV DFDFAGPAIH GSAVFGYEGW LAGYQMTFDS AKSKLTRNNF 
181:	AVGYRTGDFQ LHTNVNDGTE FGGSIYQKVC EDLDTSVNLA WTSGTNCTRF GIAAKYQLDP 
241:	TASISAKVNN SSLIGVGYTQ TLRPGVKLTL SALVDGKSIN AGGHKVGLAL ELEA