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1.B.8.1.2
VDAC3 porin.  The human orthologue forms small pores in membranes (Checchetto et al. 2014).  VDAC3 is a sensor of the oxidative state in the mitochondrial intermembrane space, and cysteyl residue modification appears to play a role (Reina et al. 2016).

Accession Number:Q60931
Protein Name:POR3 aka VDAC3
Length:283
Molecular Weight:30753.00
Species:Mus musculus (Mouse) [10090]
Location1 / Topology2 / Orientation3: Mitochondrion outer membrane1
Substrate small molecules

Cross database links:

Genevestigator: Q60931
RefSeq: NP_035826.1   
Entrez Gene ID: 22335   
Pfam: PF01459   
KEGG: mmu:22335   

Gene Ontology

GO:0005743 C:mitochondrial inner membrane
GO:0005741 C:mitochondrial outer membrane
GO:0046930 C:pore complex
GO:0000166 F:nucleotide binding
GO:0008308 F:voltage-gated anion channel activity
GO:0006820 P:anion transport
GO:0001662 P:behavioral fear response
GO:0007612 P:learning
GO:0007270 P:nerve-nerve synaptic transmission
GO:0055085 P:transmembrane transport

References (5)

[1] “A novel mouse mitochondrial voltage-dependent anion channel gene localizes to chromosome 8.”  Sampson M.J.et.al.   8812436
[2] “The transcriptional landscape of the mammalian genome.”  Carninci P.et.al.   16141072
[3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[4] “Substrate and functional diversity of lysine acetylation revealed by a proteomics survey.”  Kim S.C.et.al.   16916647
[5] “Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.”  Ballif B.A.et.al.   18034455

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MCNTPTYCDL GKAAKDVFNK GYGFGMVKID LKTKSCSGVE FSTSGHAYTD TGKASGNLET 
61:	KYKVCNYGLT FTQKWNTDNT LGTEISWENK LAEGLKLTLD TIFVPNTGKK SGKLKASYRR 
121:	DCFSLGSNVD IDFSGPTIYG WAVLAFEGWL AGYQMSFDTA KSKLSQNNFA LGYKAADFQL 
181:	HTHVNDGTEF GGSIYQKVNE RIETSINLAW TAGSNNTRFG IAAKYKLDCR TSLSAKVNNA 
241:	SLIGLGYTQT LRPGVKLTLS ALIDGKNFNA GGHKVGLGFE LEA